Fusione RM/PET nelle lesioni annessiali: Studio preliminare

Translated title of the contribution: MR-PET fusion imaging in evaluating adnexal lesions: A preliminary study

V. Fiaschetti, F. Calabria, S. Crusco, A. Meschini, F. Nucera, O. Schillaci, G. Simonetti

Research output: Contribution to journalArticle

Abstract

Purpose: The objective of this preliminary study was to examine the effects of combined magnetic resonance/positron emission tomography (MR-PET) evaluation in the morphofunctional characterisation of ovarian lesions. Materials and methods: From June 2008 to September 2010, we evaluated 24 patients (mean age 44±10 years; range 24-74) with ovarian lesions incidentally detected on ultrasonography (US) and/or multislice computed tomography (CT). All patients underwent MR imaging of the pelvis and total-body CT-PET. PET and MR images were subsequently fused at postprocessing using specific anatomical criteria. Results were compared with the histological examination. Results: Of the 24 examined lesions, 19 were malignant and five were benign on histological examination. MR, CT-PET and MR-PET sensitivity was 84%, 74% and 94%, respectively and specificity 60%, 80% and 100%, respectively. Positive (PPV) and negative predictive (NPV) values were 93% and 44% for CT-PET, 89% and 50% for MR and 100% and 83% for MR-PET, respectively. Conclusions: Pelvic MR-PET fusion imaging provides advantages in terms of sensitivity and especially specificity compared with MR imaging or CT-PET alone. The added value of this fusion imaging modality lies in combining the benefits of the morphological evaluation provided by MR imaging and the metabolic assessment provided by PET.

Translated title of the contributionMR-PET fusion imaging in evaluating adnexal lesions: A preliminary study
Original languageItalian
Pages (from-to)1288-1302
Number of pages15
JournalRadiologia Medica
Volume116
Issue number8
DOIs
Publication statusPublished - Dec 2011

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

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    Fiaschetti, V., Calabria, F., Crusco, S., Meschini, A., Nucera, F., Schillaci, O., & Simonetti, G. (2011). Fusione RM/PET nelle lesioni annessiali: Studio preliminare. Radiologia Medica, 116(8), 1288-1302. https://doi.org/10.1007/s11547-011-0720-7