MRCC management: Past, present and future

Manuela Schmidinger, Martin Gore, Camillo Porta, Sylvie Négrier, Bernard Escudier

Research output: Contribution to journalArticle


Over the last six years, the use of targeted agents has revolutionised the treatment of metastatic renal cell carcinoma (mRCC) and dramatically improved outcomes for patients.Multiple effective first-and second-line agents are now available or are in development, raising key questions and new challenges around the long-term management of mRCC. These topics were the focus of a Pfizer meeting held at the 7 th European International Kidney Cancer Symposium (EIKCS) in Vienna (4-5 May 2012), where leading European oncology experts discussed recent advances and ongoing issues in mRCC clinical practice. 'It is important for clinicians who see large numbers of patients with this rare disease to get together and share their experience and observations, for the benefit of those who only see few patients in their practice', said Professor Manuela Schmidinger, Chair of the meeting.This report offers an overview of the critical evidence and the issues of long-term mRCC management debated at the meeting. It also presents key conclusions from the recently launched report 'Europe 2012: is kidney cancer management at a crossroad?', written by a selected panel of European kidney cancer experts to highlight current barriers to the optimal treatment of mRCC patients and the development of solutions to address these.

Original languageEnglish
Pages (from-to)1-11
Number of pages11
JournalEuropean Journal of Cancer, Supplement
Issue number2
Publication statusPublished - Jun 2012


  • Metastatic renal cell carcinoma
  • MRCC
  • Sunitinib
  • Targeted agents
  • Temsirolimus
  • Therapy management

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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