Mri in hypertrophie cardiomyopathy

A morphofunctional study

Francesco Sardanelli, Giuseppe Molinari, Aldo Petillo, Carlo Ottonello, Roberto C. Parodi, Maria A. Masperone, Sandro Saitta, Massimiliano Basso, Salvatore Caponnetto

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Objective: We compared MRI with two-dimensional echocardiography (2dE) and Doppler echocardiography to determine the diagnostic role of MRI in hypertrophic cardiomyopathy (HCM). Materials and Methods: Twenty-three patients with 2dE diagnosis of HCM were examined with MRI; 12 of 23 patients were also studied by color (cDE) and continuous wave (cwDE) Doppler echocardiography. Morphologie information and diastolic heart wall thickness were obtained by SE sequences; functional study was performed by gradient echo sequences (eine MR). Results: The correlation between MR, SE sequences and 2dE was better for septal (r = 0.930, p <0.01) than for posterolateral (r = 0.739, p <0.01) wall thickness. The assessment of the distribution of the hypertrophy was changed by MR in five cases. Cine MR functional study showed a systolic subaortic signal void (dynamic obstruction) in 12 of 22 patients and a systolic left atrial Signal void (mitral regurgitation) in 17 of 22. Systolic wall thickening was studied by cine MR and 2dE in 11 patients: A good correlation was found for septum (0.01 <P <0.05) and a poor one for posterolateral wall (p > 0.05). The cine MR and cDE turbulence duration in the left ventricle and atrium showed excellent correlation (p <0.01). Good agreement was found between the duration of subaortic turbulence (cine MR or cDE) and the pressure gradient (cwDE) (p <0.01 and 0.01 <p <0.05, respectively) and between cine MR and cDE semiquantitative estimate of the mitral regurgitation (p <0.01). In all patients with subaortic MR signal void studied with cwDE, a pressure gradient was present. Conclusion: Magnetic resonance imaging can play an important role in the diagnosis of HCM after 2dE-DE.

Original languageEnglish
Pages (from-to)862-872
Number of pages11
JournalJournal of Computer Assisted Tomography
Volume17
Issue number6
Publication statusPublished - 1993

Fingerprint

Hypertrophic Cardiomyopathy
Cardiomyopathies
Doppler Echocardiography
Pressure
Mitral Valve Insufficiency
Heart Atria
Heart Ventricles
Echocardiography
Color
Magnetic Resonance Imaging

Keywords

  • Cine
  • Diseases
  • Flow dynamics
  • Heart
  • Heart
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Sardanelli, F., Molinari, G., Petillo, A., Ottonello, C., Parodi, R. C., Masperone, M. A., ... Caponnetto, S. (1993). Mri in hypertrophie cardiomyopathy: A morphofunctional study. Journal of Computer Assisted Tomography, 17(6), 862-872.

Mri in hypertrophie cardiomyopathy : A morphofunctional study. / Sardanelli, Francesco; Molinari, Giuseppe; Petillo, Aldo; Ottonello, Carlo; Parodi, Roberto C.; Masperone, Maria A.; Saitta, Sandro; Basso, Massimiliano; Caponnetto, Salvatore.

In: Journal of Computer Assisted Tomography, Vol. 17, No. 6, 1993, p. 862-872.

Research output: Contribution to journalArticle

Sardanelli, F, Molinari, G, Petillo, A, Ottonello, C, Parodi, RC, Masperone, MA, Saitta, S, Basso, M & Caponnetto, S 1993, 'Mri in hypertrophie cardiomyopathy: A morphofunctional study', Journal of Computer Assisted Tomography, vol. 17, no. 6, pp. 862-872.
Sardanelli F, Molinari G, Petillo A, Ottonello C, Parodi RC, Masperone MA et al. Mri in hypertrophie cardiomyopathy: A morphofunctional study. Journal of Computer Assisted Tomography. 1993;17(6):862-872.
Sardanelli, Francesco ; Molinari, Giuseppe ; Petillo, Aldo ; Ottonello, Carlo ; Parodi, Roberto C. ; Masperone, Maria A. ; Saitta, Sandro ; Basso, Massimiliano ; Caponnetto, Salvatore. / Mri in hypertrophie cardiomyopathy : A morphofunctional study. In: Journal of Computer Assisted Tomography. 1993 ; Vol. 17, No. 6. pp. 862-872.
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AU - Sardanelli, Francesco

AU - Molinari, Giuseppe

AU - Petillo, Aldo

AU - Ottonello, Carlo

AU - Parodi, Roberto C.

AU - Masperone, Maria A.

AU - Saitta, Sandro

AU - Basso, Massimiliano

AU - Caponnetto, Salvatore

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N2 - Objective: We compared MRI with two-dimensional echocardiography (2dE) and Doppler echocardiography to determine the diagnostic role of MRI in hypertrophic cardiomyopathy (HCM). Materials and Methods: Twenty-three patients with 2dE diagnosis of HCM were examined with MRI; 12 of 23 patients were also studied by color (cDE) and continuous wave (cwDE) Doppler echocardiography. Morphologie information and diastolic heart wall thickness were obtained by SE sequences; functional study was performed by gradient echo sequences (eine MR). Results: The correlation between MR, SE sequences and 2dE was better for septal (r = 0.930, p <0.01) than for posterolateral (r = 0.739, p <0.01) wall thickness. The assessment of the distribution of the hypertrophy was changed by MR in five cases. Cine MR functional study showed a systolic subaortic signal void (dynamic obstruction) in 12 of 22 patients and a systolic left atrial Signal void (mitral regurgitation) in 17 of 22. Systolic wall thickening was studied by cine MR and 2dE in 11 patients: A good correlation was found for septum (0.01 <P <0.05) and a poor one for posterolateral wall (p > 0.05). The cine MR and cDE turbulence duration in the left ventricle and atrium showed excellent correlation (p <0.01). Good agreement was found between the duration of subaortic turbulence (cine MR or cDE) and the pressure gradient (cwDE) (p <0.01 and 0.01

AB - Objective: We compared MRI with two-dimensional echocardiography (2dE) and Doppler echocardiography to determine the diagnostic role of MRI in hypertrophic cardiomyopathy (HCM). Materials and Methods: Twenty-three patients with 2dE diagnosis of HCM were examined with MRI; 12 of 23 patients were also studied by color (cDE) and continuous wave (cwDE) Doppler echocardiography. Morphologie information and diastolic heart wall thickness were obtained by SE sequences; functional study was performed by gradient echo sequences (eine MR). Results: The correlation between MR, SE sequences and 2dE was better for septal (r = 0.930, p <0.01) than for posterolateral (r = 0.739, p <0.01) wall thickness. The assessment of the distribution of the hypertrophy was changed by MR in five cases. Cine MR functional study showed a systolic subaortic signal void (dynamic obstruction) in 12 of 22 patients and a systolic left atrial Signal void (mitral regurgitation) in 17 of 22. Systolic wall thickening was studied by cine MR and 2dE in 11 patients: A good correlation was found for septum (0.01 <P <0.05) and a poor one for posterolateral wall (p > 0.05). The cine MR and cDE turbulence duration in the left ventricle and atrium showed excellent correlation (p <0.01). Good agreement was found between the duration of subaortic turbulence (cine MR or cDE) and the pressure gradient (cwDE) (p <0.01 and 0.01

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