MRIndex: A tool for evaluating muscle involvement in neuromuscular diseases from MRI images

Daniela Marfisi, Maria Evelina Fantacci, Guja Astrea, Filippo Maria Santorelli, Raffaele Conte, Alessandro Tonacci, Francesco Sansone

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The progress and severity of neuromuscular conditions can be monitored in several ways, most of which are invasive and, thus, poorly acceptable, for the patient. Among the least obtrusive solutions, the use of muscular magnetic resonance imaging is gaining importance in last decades, therefore becoming the elective methodology for defining the muscular involvement in such conditions. However, subjectivity is always quite frequent in the interpretation of biomedical images, and the diagnosis is often demanded to the experience of the clinician's eye. With MRIndex, a novel tool for the automated analysis of muscular magnetic resonance images, a quantitative 'picture' of the muscular involvement in neuromuscular conditions is defined, stemming from the definition of fat infiltration within the muscular tissue, well-known biomarker for disease severity. The solution is currently used at clinics and preliminary at-a-glance results are quite promising. If such evidence is confirmed on larger cohorts and with a more robust statistical approach, the tool can represent a groundbreaking alternative in current clinical practice, possibly bringing to a more objective definition of the clinical status of a patient and helping in the personalization of the treatment, possibly improving their outcome.

Original languageEnglish
Title of host publication2019 IEEE 23rd International Symposium on Consumer Technologies, ISCT 2019
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages287-290
Number of pages4
ISBN (Electronic)9781728135700
DOIs
Publication statusPublished - Jun 2019
Event23rd IEEE International Symposium on Consumer Technologies, ISCT 2019 - Ancona, Italy
Duration: Jun 19 2019Jun 21 2019

Publication series

Name2019 IEEE 23rd International Symposium on Consumer Technologies, ISCT 2019

Conference

Conference23rd IEEE International Symposium on Consumer Technologies, ISCT 2019
CountryItaly
CityAncona
Period6/19/196/21/19

Keywords

  • diagnosis
  • healthcare
  • ICT
  • imaging
  • muscular MRI
  • neuromuscular diseases

ASJC Scopus subject areas

  • Instrumentation
  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Media Technology

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