mtDNA A3243G MELAS mutation is not associated with multigenerational female migraine

Maria Gabriella Buzzi, G. Di Gennaro, M. D'Onofrio, O. Ciccarelli, F. M. Santorelli, D. Fortini, G. Nappi, F. Nicoletti, C. Casali

Research output: Contribution to journalArticle

Abstract

The authors searched for mitochondrial DNA (mtDNA) A3243G mutation in peripheral blood leukocytes from female migraine patients with pure matrilinear history of migraine along two or three generations. The current study was designed to exclude any male transmission of the disease. The mutation was absent in all patients. We conclude that mtDNA A3243G mutation does not contribute to the pathogenesis of pure matrilinear multigenerational migraine with or without aura.

Original languageEnglish
Pages (from-to)1005-1007
Number of pages3
JournalNeurology
Volume54
Issue number4
Publication statusPublished - Feb 22 2000

Keywords

  • Female
  • MELAS
  • Migraine

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'mtDNA A3243G MELAS mutation is not associated with multigenerational female migraine'. Together they form a unique fingerprint.

  • Cite this

    Buzzi, M. G., Di Gennaro, G., D'Onofrio, M., Ciccarelli, O., Santorelli, F. M., Fortini, D., Nappi, G., Nicoletti, F., & Casali, C. (2000). mtDNA A3243G MELAS mutation is not associated with multigenerational female migraine. Neurology, 54(4), 1005-1007.