Mucin-secreting cellular ependymoma: A light and electron microscopy study

Giovanna Cenacchi, Isabella Morra, Marco Forni, Felice Giangaspero

Research output: Contribution to journalArticlepeer-review


Mucin accumulation in ependymomas is thought to be limited to the myxopapillary variant and represents an important diagnostic feature. Similarly, signet-ring cells in ependymomas have been shown by electron microscopy to represent microrosette instead of mucin secretion. This study describes an infratentorial ependymoma largely composed of mucinous areas and signet-ring cells. The ependymal nature of mucin-secreting cells was confirmed by ultrastructural analysis. This case widens the variable spectrum of ependymal morphology. The value of electron microscopy in differentiating central nervous system neoplasms showing mucous secretion is stressed.

Original languageEnglish
Pages (from-to)319-323
Number of pages5
JournalUltrastructural Pathology
Issue number5
Publication statusPublished - 1999


  • Central nervous system tumor
  • Ependymoma
  • Mucin-secreting cell
  • Transmission electron microscopy

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Instrumentation
  • Structural Biology


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