Multicentre, cross-sectional study of ventricular arrhythmias in chronically haemodialysed patients

B. Redaelli, A. Cavalli, R. Latini, A. P. Maggioni, G. Mingardi, G. Osculati, S. Sforzini, G. Tognoni, A. Vincenti, A. Volpi, L. Conforti, L. Gondoni, E. Santoro, M. Rocchetti

Research output: Contribution to journalArticlepeer-review

Abstract

127 patients on ambulatory in-hospital haemodialysis (HD) were randomly selected from 13 centres. The prevalence of ischaemic heart disease was 14%, 17% had left ventricular dysfunction, and 37% had left ventricular hypertrophy. Ventricular arrhythmias, assessed by continuous 48 h Holter monitoring, were present in 76% of patients. 29% had ≥2 premature ventricular complexes (PVC)/h; 21% had Lown classes 4A or B; and 6% had ≥3 consecutive beats of ventricular tachycardia. Risk factors for ventricular arrhythmias were age ≥55 yr and left ventricular dysfunction, independent of age. The frequency of ventricular arrhythmias rose significantly during the third hour of HD, and this effect lasted for at least 5 h after dialysis, and was associated with age ≥55 yr, left ventricular dysfunction, and the presence of ventricular arrhythmias before dialysis. Ventricular arrhythmias are present in a large proportion of patients with end-stage renal failure and HD has an arrhythmogenic effect.

Original languageEnglish
Pages (from-to)305-309
Number of pages5
JournalLancet
Volume2
Issue number8606
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Medicine(all)

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