Multicentre retrospective study on endoscopic ultrasound complications

E. Buscarini, C. De Angelis, P. G. Arcidiacono, R. Rocca, G. Lupinacci, R. Manta, P. Carucci, A. Repici, S. Carrara, D. Vallisa, L. Buscarini, F. Cosentino, A. Pera, M. Rizzetto, P. A. Testoni, A. Zambelli

Research output: Contribution to journalArticlepeer-review


Background: Endoscopic ultrasonography, both conventional and interventional, has been used increasingly during the past 20 years and is deemed a safe technique. Its complication rate, however, has been studied to only a limited extent. This multicentre investigation sought to establish the complication rate for a large number of endoscopic ultrasonography procedures. Methods: By means of a questionnaire, we collected data from six centres on the number of endoscopic ultrasonography examinations performed and divided them into conventional and interventional examinations of the upper and lower gastrointestinal tract. Information was obtained on technical modalities such as instruments and sedation and, for interventional endoscopic ultrasonography, indications, pre-procedural exams and technical details (needle calibre, number of passes) had to be specified. Complications were classified as mild, moderate, severe or fatal and their onset as immediate, early or late. Variables that entered into the analysis of complication rate included type of endoscopic ultrasonography instrument used, type and site of lesion biopsied, number of needle passes and operator experience. Results: Eleven thousand five hundred thirty nine endoscopic ultrasonographic procedures were reported, of which 10,731 were conventional and 808 interventional. No deaths occurred; there were 14 (0.12%) complications, 5 (0.046%) of them following conventional endoscopic ultrasonography and 9 (1.11%) after interventional endoscopic ultrasonography. Seven complications were mild, four moderate and three severe. Conclusions: Both conventional and interventional endoscopic ultrasonography were confirmed to be acceptably safe techniques.

Original languageEnglish
Pages (from-to)762-767
Number of pages6
JournalDigestive and Liver Disease
Issue number10
Publication statusPublished - Oct 2006


  • Complications
  • Endoscopic ultrasonography
  • EUS
  • Training

ASJC Scopus subject areas

  • Gastroenterology


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