Multicentric and multifocal primary cerebral tumours. Methods of diagnosis and treatment

M. Salvati, L. Cervoni, P. Celli, R. Caruso, F. M. Gagliardi

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Forty patients with multifocal and multicentric cerebral tumours were retrospectively studied. The patients were divided into two groups: ten patients with multicentric tumours (group A), and 30 patients with multifocal tumours. As far as their preoperative clinical history and the incidence of the various symptoms and signs are concerned, there were no significant differences between the two groups. CT permitted a correct diagnosis in 90% of the cases. All of the patients underwent the removal of the tumour(s) and received radiotherapy; 30 patients also received chemotherapy. In group A, nine patients died and one was lost to follow-up one year after treatment; the average survival was ten months from the appearance of the multicentric tumour. In group B, 29 patients died and one is still alive two years after treatment; the average survival was six months. We consider the problems of diagnosis and the longterm follow-up of patients.

Original languageEnglish
Pages (from-to)17-20
Number of pages4
JournalItalian Journal of Neurological Sciences
Issue number1
Publication statusPublished - 1997


  • Multicentric glioma
  • Multifocal tumour
  • Multiple glioma

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology


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