Multidimensional Prognostic Index predicts mortality and length of stay during hospitalization in the older patients: A multicenter prospective study

Stefano Volpato, Salvatore Bazzano, Andrea Fontana, Luigi Ferrucci, Alberto Pilotto

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The Multidimensional Prognostic Index (MPI) is a validated predictive tool for long-term mortality based on information collected in a standardized Comprehensive Geriatric Assessment. We investigated whether the MPI is an effective predictor of intrahospital mortality and length of hospital stay after admission to acute geriatric wards. Methods: Prospective study of 1,178 older patients (702 women and 476 men, 85.0 ± 6.8 years) admitted to 20 geriatrics units. Within 48 hours from admission, the MPI, according to an earlier validated algorithm, was calculated. Subjects were divided into three groups of MPI score, low-risk (MPI-1 value. 0.33), moderate-risk (MPI-2 value 0.34.0.66), and severe-risk of mortality (MPI-3 value. 0.67), on the basis of earlier established cut-offs. Associations with in-hospital mortality and length of stay were examined using multivariable Cox regression models and adjusted Poisson linear mixed-effects models, respectively. Results: At admission, 23.6% subjects had a MPI-1 score, 33.8% had a MPI-2 score, and 42.6% had a MPI-3 score. Subjects with higher MPI score at admission were older (p

Original languageEnglish
Pages (from-to)325-331
Number of pages7
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume70
Issue number3
DOIs
Publication statusPublished - 2015

Keywords

  • Aging
  • Hospital
  • Mortality
  • MPI
  • Prognosis

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

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