Multifocal, persistent cardiac uptake of [18-F]-fluoro-deoxy-glucose detected by positron emission tomography in patients with acute myocardial infarction

Cosmo Godino, Cristina Messa, Luigi Gianolli, Claudio Landoni, Alberto Margonato, Michela Cera, Coli Stefano, Domenico Cianflone, Ferruccio Fazio, Attilio Maseri

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Inflammation appears to be important in the pathogenesis of acute myocardial infarction (AMI). Methods and Results: Cardiac [18-F]-fluoro-deoxy-glucose (FDG) uptake by positron emission tomography/computed tomography (PET/CT)-scan was investigated in 12 fasting patients with first AMI (FAMI) single-vessel disease after successful primary percutaneous coronary intervention and at 9 weeks follow-up, and in 12 controls. The average FDG uptake (aFDGu) of the 28 left ventricular (LV) wall segments defined on the PET/CT images of the 12 FAMI patients was 1.28±0.57-fold higher than the activity present in the LV cavity. By contrast, the aFDGu of the 12 controls was 0.70±22 (p

Original languageEnglish
Pages (from-to)1821-1828
Number of pages8
JournalCirculation Journal
Volume72
Issue number11
DOIs
Publication statusPublished - 2008

Keywords

  • FDG uptake
  • Inflammation
  • Myocardial infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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