Multimodal evoked potentials to assess the evolution of multiple sclerosis

A longitudinal study

L. Leocani, M. Rovaris, F. M. Boneschi, S. Medaglini, P. Rossi, V. Martinelli, S. Amadio, G. Comi

Research output: Contribution to journalArticle

96 Citations (Scopus)

Abstract

Background: Evoked potentials are used in the functional assessment of sensory and motor pathways. Their usefulness in monitoring the evolution of multiple sclerosis has not been fully clarified. Objective: The aim of this longitudinal study was to examine the usefulness of multimodal evoked potential in predicting paraclinical outcomes of disease severity and as a prognostic marker in multiple sclerosis. Methods: Eighty four patients with clinically definite multiple sclerosis underwent Expanded Disability Status Scale (EDSS) and functional system scoring at study entry and after a mean (standard deviation) follow-up of 30.5 (11.7) months. Sensory and motor evoked potentials were obtained in all patients at study entry and at follow-up in 64 of them, and quantified according to a conventional score. Results: Cross-sectionally, the severity of each evoked potential score significantly correlated with the corresponding functional system (0.32

Original languageEnglish
Pages (from-to)1030-1035
Number of pages6
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume77
Issue number9
DOIs
Publication statusPublished - Sep 2006

Fingerprint

Evoked Potentials
Multiple Sclerosis
Longitudinal Studies
Efferent Pathways
Motor Evoked Potentials

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

Cite this

Multimodal evoked potentials to assess the evolution of multiple sclerosis : A longitudinal study. / Leocani, L.; Rovaris, M.; Boneschi, F. M.; Medaglini, S.; Rossi, P.; Martinelli, V.; Amadio, S.; Comi, G.

In: Journal of Neurology, Neurosurgery and Psychiatry, Vol. 77, No. 9, 09.2006, p. 1030-1035.

Research output: Contribution to journalArticle

@article{0d26afe5e616477e93faf0b60001a1d2,
title = "Multimodal evoked potentials to assess the evolution of multiple sclerosis: A longitudinal study",
abstract = "Background: Evoked potentials are used in the functional assessment of sensory and motor pathways. Their usefulness in monitoring the evolution of multiple sclerosis has not been fully clarified. Objective: The aim of this longitudinal study was to examine the usefulness of multimodal evoked potential in predicting paraclinical outcomes of disease severity and as a prognostic marker in multiple sclerosis. Methods: Eighty four patients with clinically definite multiple sclerosis underwent Expanded Disability Status Scale (EDSS) and functional system scoring at study entry and after a mean (standard deviation) follow-up of 30.5 (11.7) months. Sensory and motor evoked potentials were obtained in all patients at study entry and at follow-up in 64 of them, and quantified according to a conventional score. Results: Cross-sectionally, the severity of each evoked potential score significantly correlated with the corresponding functional system (0.32",
author = "L. Leocani and M. Rovaris and Boneschi, {F. M.} and S. Medaglini and P. Rossi and V. Martinelli and S. Amadio and G. Comi",
year = "2006",
month = "9",
doi = "10.1136/jnnp.2005.086280",
language = "English",
volume = "77",
pages = "1030--1035",
journal = "Journal of Neurology, Neurosurgery and Psychiatry",
issn = "0022-3050",
publisher = "BMJ Publishing Group",
number = "9",

}

TY - JOUR

T1 - Multimodal evoked potentials to assess the evolution of multiple sclerosis

T2 - A longitudinal study

AU - Leocani, L.

AU - Rovaris, M.

AU - Boneschi, F. M.

AU - Medaglini, S.

AU - Rossi, P.

AU - Martinelli, V.

AU - Amadio, S.

AU - Comi, G.

PY - 2006/9

Y1 - 2006/9

N2 - Background: Evoked potentials are used in the functional assessment of sensory and motor pathways. Their usefulness in monitoring the evolution of multiple sclerosis has not been fully clarified. Objective: The aim of this longitudinal study was to examine the usefulness of multimodal evoked potential in predicting paraclinical outcomes of disease severity and as a prognostic marker in multiple sclerosis. Methods: Eighty four patients with clinically definite multiple sclerosis underwent Expanded Disability Status Scale (EDSS) and functional system scoring at study entry and after a mean (standard deviation) follow-up of 30.5 (11.7) months. Sensory and motor evoked potentials were obtained in all patients at study entry and at follow-up in 64 of them, and quantified according to a conventional score. Results: Cross-sectionally, the severity of each evoked potential score significantly correlated with the corresponding functional system (0.32

AB - Background: Evoked potentials are used in the functional assessment of sensory and motor pathways. Their usefulness in monitoring the evolution of multiple sclerosis has not been fully clarified. Objective: The aim of this longitudinal study was to examine the usefulness of multimodal evoked potential in predicting paraclinical outcomes of disease severity and as a prognostic marker in multiple sclerosis. Methods: Eighty four patients with clinically definite multiple sclerosis underwent Expanded Disability Status Scale (EDSS) and functional system scoring at study entry and after a mean (standard deviation) follow-up of 30.5 (11.7) months. Sensory and motor evoked potentials were obtained in all patients at study entry and at follow-up in 64 of them, and quantified according to a conventional score. Results: Cross-sectionally, the severity of each evoked potential score significantly correlated with the corresponding functional system (0.32

UR - http://www.scopus.com/inward/record.url?scp=33747406972&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33747406972&partnerID=8YFLogxK

U2 - 10.1136/jnnp.2005.086280

DO - 10.1136/jnnp.2005.086280

M3 - Article

VL - 77

SP - 1030

EP - 1035

JO - Journal of Neurology, Neurosurgery and Psychiatry

JF - Journal of Neurology, Neurosurgery and Psychiatry

SN - 0022-3050

IS - 9

ER -