Multimodal fusion of biomedical data at different temporal and dimensional scales

Marco Viceconti, Gordon Clapworthy, Debora Testi, Fulvia Taddei, Nigel McFarlane

Research output: Contribution to journalArticlepeer-review


The introduction of integrative approaches to biomedical research (integrative biology, physiome, Virtual Physiological Human, etc.) poses original problems to computer aided medicine: the need to operate with large amounts of data that are strongly heterogeneous in structure, format and even in the knowledge domain that generated them; the need to integrate all of these data into a coherent whole; the further complication imposed by the fact that more and more frequently these data are captured at very different dimensional and/or temporal scales. The present study describes a first attempt at providing an interactive visualisation environment for homogeneous biomedical data defined over radically different spatial or temporal scales. In particular, we describe new strategies for the management of the dimensional information of highly heterogeneous data types; the management of temporal multiscaling; for 3D unstructured spatial multiscale visualisation and the related interaction paradigms and user interface. Preliminary results with a prototype implementation based on the OpenMAF application framework ( indicate that it is possible to develop effective environments for interactive visualisation of multiscale biomedical data.

Original languageEnglish
Pages (from-to)227-237
Number of pages11
JournalComputer Methods and Programs in Biomedicine
Issue number3
Publication statusPublished - Jun 2011


  • Integrative biomedical research
  • Multiscale visualisation
  • Virtual Physiological Human

ASJC Scopus subject areas

  • Computer Science Applications
  • Software
  • Health Informatics


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