Multimodal integration of high resolution EEG and functional magnetic resonance: A simulation study

Fabio Babiloni, Claudio Babiloni, Filippo Carducci, Leonardo Angelone, Cosimo Del Gratta, Gian Luca Romani, Paolo Maria Rossini, Febo Cincotti

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this simulation study, we would like to address some questions related to the use of fMRI a priori constraints in the estimation of the cortical source current density. Namely, we would like to assess the utility to include information as estimated from event-related and block-design fMRI, by using as the dependent variable the correlation between the imposed and the estimated waveforms at the level of cortical region of interests (ROI). A realistic head and cortical surface model was used. Factors used were i) the signal to noise ratio of the scalp simulated data (SNR); ii) the particular inverse operator used to estimate the cortical source activity from the simulated scalp data (INVERSE); iii) the strength of the fMRI priors in the estimation of the current activity (K). Analysis of Variance (ANOVA) results revealed that all the considered factors (SNR, INVERSE, K) significantly afflicts the correlation between the estimated and the simulated cortical activity. For the ROIs analyzed in which a presence of fMRI hotspots were simulated, it was observed that the best estimation of cortical source currents were performed with the inverse operator that use the event-related fMRI information. When the ROI analyzed do not present fMRI hotspots, both minimum norm and fMRI-based inverse operators return statistically equivalent correlation values. Such results open the avenue for the use of fMRI-based inverse operator in the estimation of cortical current strengths from motor and cognitive task in the human brain.

Original languageEnglish
Title of host publicationAnnual Reports of the Research Reactor Institute, Kyoto University
Pages986-989
Number of pages4
Volume1
Publication statusPublished - 2001
Event23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Istanbul, Turkey
Duration: Oct 25 2001Oct 28 2001

Other

Other23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CountryTurkey
CityIstanbul
Period10/25/0110/28/01

Fingerprint

Magnetic resonance
Electroencephalography
Magnetic Resonance Imaging
Analysis of variance (ANOVA)
Mathematical operators
Brain
Signal to noise ratio
Current density

ASJC Scopus subject areas

  • Energy Engineering and Power Technology
  • Mechanical Engineering

Cite this

Babiloni, F., Babiloni, C., Carducci, F., Angelone, L., Del Gratta, C., Romani, G. L., ... Cincotti, F. (2001). Multimodal integration of high resolution EEG and functional magnetic resonance: A simulation study. In Annual Reports of the Research Reactor Institute, Kyoto University (Vol. 1, pp. 986-989)

Multimodal integration of high resolution EEG and functional magnetic resonance : A simulation study. / Babiloni, Fabio; Babiloni, Claudio; Carducci, Filippo; Angelone, Leonardo; Del Gratta, Cosimo; Romani, Gian Luca; Rossini, Paolo Maria; Cincotti, Febo.

Annual Reports of the Research Reactor Institute, Kyoto University. Vol. 1 2001. p. 986-989.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Babiloni, F, Babiloni, C, Carducci, F, Angelone, L, Del Gratta, C, Romani, GL, Rossini, PM & Cincotti, F 2001, Multimodal integration of high resolution EEG and functional magnetic resonance: A simulation study. in Annual Reports of the Research Reactor Institute, Kyoto University. vol. 1, pp. 986-989, 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Istanbul, Turkey, 10/25/01.
Babiloni F, Babiloni C, Carducci F, Angelone L, Del Gratta C, Romani GL et al. Multimodal integration of high resolution EEG and functional magnetic resonance: A simulation study. In Annual Reports of the Research Reactor Institute, Kyoto University. Vol. 1. 2001. p. 986-989
Babiloni, Fabio ; Babiloni, Claudio ; Carducci, Filippo ; Angelone, Leonardo ; Del Gratta, Cosimo ; Romani, Gian Luca ; Rossini, Paolo Maria ; Cincotti, Febo. / Multimodal integration of high resolution EEG and functional magnetic resonance : A simulation study. Annual Reports of the Research Reactor Institute, Kyoto University. Vol. 1 2001. pp. 986-989
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