TY - JOUR
T1 - Multimodality imaging in pulmonary hypertension
AU - Bossone, Eduardo
AU - Dellegrottaglie, Santo
AU - Patel, Smita
AU - Grunig, Ekkehard
AU - D'Andrea, Antonello
AU - Ferrara, Francesco
AU - Gargiulo, Paola
AU - D'Alto, Michele
AU - Soricelli, Andrea
AU - Cittadini, Antonio
AU - Sanz, Javier
AU - Perrone-Filardi, Pasquale
AU - Rubenfire, Melvyn
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Pulmonary hypertension (PH) is a pathophysiological condition defined as an increase in mean pulmonary artery pressure of ≥ 25 mm Hg at rest. Although right heart catheterization remains an essential step in the diagnostic algorithm-particularly for pulmonary arterial hypertension-noninvasive multimodality imaging plays an important role in defining the cause, assessing outcome, monitoring the efficacy of specific therapeutic interventions, and detecting the preclinical stage of disease. We review the role of multimodality imaging in the evaluation of PH-including echocardiography, chest computed tomography, cardiovascular magnetic resonance imaging, and nuclear imaging-the choice of which depends on individual patient-based indications provided by the clinical team in accordance with current guidelines, also taking into account institutional expertise, patient safety and convenience, and repeatability. Recent advances in cardiac imaging (3-dimensional echocardiography and strain imaging, tissue characterization, and 18F-fluorodeoxyglucose positron emission tomography) may provide new insights into the pathophysiological characteristics of the right heart-pulmonary circulation unit.
AB - Pulmonary hypertension (PH) is a pathophysiological condition defined as an increase in mean pulmonary artery pressure of ≥ 25 mm Hg at rest. Although right heart catheterization remains an essential step in the diagnostic algorithm-particularly for pulmonary arterial hypertension-noninvasive multimodality imaging plays an important role in defining the cause, assessing outcome, monitoring the efficacy of specific therapeutic interventions, and detecting the preclinical stage of disease. We review the role of multimodality imaging in the evaluation of PH-including echocardiography, chest computed tomography, cardiovascular magnetic resonance imaging, and nuclear imaging-the choice of which depends on individual patient-based indications provided by the clinical team in accordance with current guidelines, also taking into account institutional expertise, patient safety and convenience, and repeatability. Recent advances in cardiac imaging (3-dimensional echocardiography and strain imaging, tissue characterization, and 18F-fluorodeoxyglucose positron emission tomography) may provide new insights into the pathophysiological characteristics of the right heart-pulmonary circulation unit.
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U2 - 10.1016/j.cjca.2015.02.012
DO - 10.1016/j.cjca.2015.02.012
M3 - Article
C2 - 25840095
AN - SCOPUS:84965107509
VL - 31
SP - 440
EP - 459
JO - Canadian Journal of Cardiology
JF - Canadian Journal of Cardiology
SN - 0828-282X
IS - 4
ER -