Multimodality imaging of adult rhabdomyosarcoma: the added value of hybrid imaging

Research output: Contribution to journalReview articlepeer-review


Rhabdomyosarcoma (RMS) represents more than 50% of paediatric soft tissue tumours. Conversely, it is extremely rare among adults, where it shows peculiar biological and clinical features that are still poorly investigated. RMS patients should be referred to a Sarcoma Centre, where the contribution of experienced radiologists plays a relevant role in the diagnostic assessment of the disease, including precise localisation, staging, image-guided biopsy, response evaluation after treatment and follow-up. Besides CT and MRI, hybrid imaging including positron emission tomography (PET)/CT and PET/MRI are giving an increasing contribution to provide functional insights about tumour biology and to improve the diagnostic accuracy of the imaging work-up. This review paper provides a revision of the pathology, clinical and radiological features of adult RMS, with a particular focus on the growing role of hybrid PET-based imaging.

Original languageEnglish
Pages (from-to)20200250
JournalThe British journal of radiology
Issue number1112
Publication statusPublished - Aug 2020


  • Humans
  • Magnetic Resonance Imaging
  • Multimodal Imaging/methods
  • Positron Emission Tomography Computed Tomography
  • Rhabdomyosarcoma/diagnostic imaging
  • Soft Tissue Neoplasms/diagnostic imaging
  • Tomography, X-Ray Computed


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