TY - JOUR
T1 - Multimodality imaging of adult rhabdomyosarcoma
T2 - the added value of hybrid imaging
AU - Gennaro, Nicolò
AU - Marrari, Andrea
AU - Renne, Salvatore Lorenzo
AU - Cananzi, Ferdinando Carlo Maria
AU - Quagliuolo, Vittorio Lorenzo
AU - Di Brina, Lucia
AU - Scorsetti, Marta
AU - Pepe, Giovanna
AU - Chiti, Arturo
AU - Santoro, Armando
AU - Balzarini, Luca
AU - Politi, Letterio Salvatore
AU - Bertuzzi, Alexia Francesca
PY - 2020/8
Y1 - 2020/8
N2 - Rhabdomyosarcoma (RMS) represents more than 50% of paediatric soft tissue tumours. Conversely, it is extremely rare among adults, where it shows peculiar biological and clinical features that are still poorly investigated. RMS patients should be referred to a Sarcoma Centre, where the contribution of experienced radiologists plays a relevant role in the diagnostic assessment of the disease, including precise localisation, staging, image-guided biopsy, response evaluation after treatment and follow-up. Besides CT and MRI, hybrid imaging including positron emission tomography (PET)/CT and PET/MRI are giving an increasing contribution to provide functional insights about tumour biology and to improve the diagnostic accuracy of the imaging work-up. This review paper provides a revision of the pathology, clinical and radiological features of adult RMS, with a particular focus on the growing role of hybrid PET-based imaging.
AB - Rhabdomyosarcoma (RMS) represents more than 50% of paediatric soft tissue tumours. Conversely, it is extremely rare among adults, where it shows peculiar biological and clinical features that are still poorly investigated. RMS patients should be referred to a Sarcoma Centre, where the contribution of experienced radiologists plays a relevant role in the diagnostic assessment of the disease, including precise localisation, staging, image-guided biopsy, response evaluation after treatment and follow-up. Besides CT and MRI, hybrid imaging including positron emission tomography (PET)/CT and PET/MRI are giving an increasing contribution to provide functional insights about tumour biology and to improve the diagnostic accuracy of the imaging work-up. This review paper provides a revision of the pathology, clinical and radiological features of adult RMS, with a particular focus on the growing role of hybrid PET-based imaging.
KW - Humans
KW - Magnetic Resonance Imaging
KW - Multimodal Imaging/methods
KW - Positron Emission Tomography Computed Tomography
KW - Rhabdomyosarcoma/diagnostic imaging
KW - Soft Tissue Neoplasms/diagnostic imaging
KW - Tomography, X-Ray Computed
U2 - 10.1259/bjr.20200250
DO - 10.1259/bjr.20200250
M3 - Review article
C2 - 32559113
VL - 93
SP - 20200250
JO - British Journal of Radiology
JF - British Journal of Radiology
SN - 0007-1285
IS - 1112
ER -