Multinucleate cell angiohistiocytoma

G. Annessi, G. Girolomoni, A. Giannetti

Research output: Contribution to journalArticle

Abstract

We report a case of multinucleate cell angiohistiocytoma occurring in a 50-year-old woman and presenting with a 4-year history of asymptomatic red papules on the face. Histologically, there was a dermal vascular proliferation associated with numerous multinucleate cells. Immunohistochemical studies showed vascular spaces surrounded with mature vascular endothelial cells, and the presence of numerous interstitial factor XIIIa+ cells. Multinucleate cells exhibited intermediate filaments of the vimentin type, but were not stained by endothelial cell or macrophage markers, and were factor XIIIa-. This condition must be addressed in the differential diagnosis of other skin vascular proliferations, such as Kaposi's sarcoma and angiofibromas.

Original languageEnglish
Pages (from-to)340-344
Number of pages5
JournalAmerican Journal of Dermatopathology
Volume14
Issue number4
Publication statusPublished - 1992

Fingerprint

Factor XIIIa
Blood Vessels
Endothelial Cells
Angiofibroma
Skin
Intermediate Filaments
Kaposi's Sarcoma
Vimentin
Differential Diagnosis
Macrophages

Keywords

  • Angiofibroma
  • Multinucleate cell angiohistiocytoma
  • Skin
  • Vascular tumor

ASJC Scopus subject areas

  • Dermatology
  • Pathology and Forensic Medicine

Cite this

Annessi, G., Girolomoni, G., & Giannetti, A. (1992). Multinucleate cell angiohistiocytoma. American Journal of Dermatopathology, 14(4), 340-344.

Multinucleate cell angiohistiocytoma. / Annessi, G.; Girolomoni, G.; Giannetti, A.

In: American Journal of Dermatopathology, Vol. 14, No. 4, 1992, p. 340-344.

Research output: Contribution to journalArticle

Annessi, G, Girolomoni, G & Giannetti, A 1992, 'Multinucleate cell angiohistiocytoma', American Journal of Dermatopathology, vol. 14, no. 4, pp. 340-344.
Annessi, G. ; Girolomoni, G. ; Giannetti, A. / Multinucleate cell angiohistiocytoma. In: American Journal of Dermatopathology. 1992 ; Vol. 14, No. 4. pp. 340-344.
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