The authors present a case of Multinucleate Cell Angiohistiocytoma (MCAH), that appeared in multiple lesions on the face of a male subject, and describe its clinical, histological and immunohistological features. MCAH is an anatomo-clinical entity which has a distinct nosologic autonomy. The main clinical features are papular-nodular lesions on the face and limbs, while, histologically, the lesions present a vascular proliferation with multinucleated cells in the contest of mid dermis. Since MCAH presented negative stain for anti-CD68 and anti-Factor XIIIa antibodies and positivity for anti-Vimentin antibodies, these findings are in agreement with a fibroblastic origin of the multinucleated cells.
|Translated title of the contribution||Multinucleate cell angiohistiocytoma|
|Number of pages||3|
|Journal||Giornale Italiano di Dermatologia e Venereologia|
|Publication status||Published - 1997|
ASJC Scopus subject areas