Angioistiocitoma a cellule multinucleate

Translated title of the contribution: Multinucleate cell angiohistiocytoma

P. Donati, F. Pinto, M. C. Giuliano, G. Sacerdoti, M. Fazio

Research output: Contribution to journalArticlepeer-review


The authors present a case of Multinucleate Cell Angiohistiocytoma (MCAH), that appeared in multiple lesions on the face of a male subject, and describe its clinical, histological and immunohistological features. MCAH is an anatomo-clinical entity which has a distinct nosologic autonomy. The main clinical features are papular-nodular lesions on the face and limbs, while, histologically, the lesions present a vascular proliferation with multinucleated cells in the contest of mid dermis. Since MCAH presented negative stain for anti-CD68 and anti-Factor XIIIa antibodies and positivity for anti-Vimentin antibodies, these findings are in agreement with a fibroblastic origin of the multinucleated cells.

Translated title of the contributionMultinucleate cell angiohistiocytoma
Original languageItalian
Pages (from-to)55-57
Number of pages3
JournalGiornale Italiano di Dermatologia e Venereologia
Issue number1
Publication statusPublished - 1997

ASJC Scopus subject areas

  • Dermatology


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