Multiparametric MRI in a patient with adult-onset leukoencephalopathy with vanishing white matter

A. Gallo, M. A. Rocca, A. Falini, C. Scaglione, F. Salvi, A. Gambini, L. Guerrini, M. Mascalchi, J. C. Pronk, M. S. Van Der Knaap, Massimo Filippi

Research output: Contribution to journalArticle

Abstract

This is a multiparametric MR study of the first reported patient with adult-onset genetically confirmed vanishing white matter (VWM) disease. It shows that, despite the presence of a severe and diffuse damage of the brain WM, brain gray matter, and cervical cord tissue, the cortical adaptive capacities were relatively preserved. Interpatient variability of brain plasticity may contribute to the known phenotypic variation of patients with VWM disease.

Original languageEnglish
Pages (from-to)323-326
Number of pages4
JournalNeurology
Volume62
Issue number2
Publication statusPublished - Jan 27 2004

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Multiparametric MRI in a patient with adult-onset leukoencephalopathy with vanishing white matter'. Together they form a unique fingerprint.

  • Cite this

    Gallo, A., Rocca, M. A., Falini, A., Scaglione, C., Salvi, F., Gambini, A., Guerrini, L., Mascalchi, M., Pronk, J. C., Van Der Knaap, M. S., & Filippi, M. (2004). Multiparametric MRI in a patient with adult-onset leukoencephalopathy with vanishing white matter. Neurology, 62(2), 323-326.