TY - JOUR
T1 - Multiple coronary artery thrombosis in 5,10-methylenetetrahydrofolate reductase gene mutation
AU - Campanile, Alfonso
AU - Sozzi, Fabiola B.
AU - Danzi, Gian Battista
PY - 2011
Y1 - 2011
N2 - A 42-year-old man presented at our attention with chest pain. His cardiac risk factors were smoking habit and family history of coronary artery disease. At the ECG, a mild ST-segment elevation in the inferior leads was shown. A normal left ventricular function was demonstrated at the echocardiography. An emergency coronary angiography was performed, and an extensive thrombosis of the right coronary artery and midleft anterior descending coronary artery was visualized. A primary angioplasty with thrombus aspiration and direct stenting of both sites followed. Biochemical analysis revealed a high plasma homocysteine level with a homozygotic anomaly of the 5,10-methylenetetrahydrofolate reductase. Currently, a nine-month followup negative for cardiac events is recorded.
AB - A 42-year-old man presented at our attention with chest pain. His cardiac risk factors were smoking habit and family history of coronary artery disease. At the ECG, a mild ST-segment elevation in the inferior leads was shown. A normal left ventricular function was demonstrated at the echocardiography. An emergency coronary angiography was performed, and an extensive thrombosis of the right coronary artery and midleft anterior descending coronary artery was visualized. A primary angioplasty with thrombus aspiration and direct stenting of both sites followed. Biochemical analysis revealed a high plasma homocysteine level with a homozygotic anomaly of the 5,10-methylenetetrahydrofolate reductase. Currently, a nine-month followup negative for cardiac events is recorded.
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U2 - 10.4061/2011/856479
DO - 10.4061/2011/856479
M3 - Article
C2 - 21918725
AN - SCOPUS:81555214514
VL - 1
JO - Cardiology Research and Practice
JF - Cardiology Research and Practice
SN - 2090-0597
IS - 1
M1 - 856479
ER -