Multiple lines of chemotherapy are the main risk factor for severe infections in patients with chronic lymphocytic leukemia with febrile episodes

Alfredo Molteni, Annamaria Nosari, Marco Montillo, Anna Cafro, Catherine Klersy, Enrica Morra

Research output: Contribution to journalArticlepeer-review

Abstract

We report on febrile episodes occurring among 379 patients affected by chronic lymphocytic leukemia, observed from 1984 to 2002. One hundred and twenty eight patients (33.7%) developed 341 febrile episodes, of which 251 were documented infections (82 severe and 169 moderate). Among various risk factors, only previous treatment with multiple regimens of chemotherapy was associated with severity of infection (p=0.0005).

Original languageEnglish
Pages (from-to)1145-1147
Number of pages3
JournalHaematologica
Volume90
Issue number8
Publication statusPublished - Aug 2005

Keywords

  • Chronic lymphocytic leukemia
  • Febrile episodes
  • FUO
  • Infections

ASJC Scopus subject areas

  • Hematology

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