Translated title of the contribution: Multiple primary metachronous lung cancers

V. Cangemi, P. Volpino, N. D'Andrea, G. Galati, S. Consolo, A. Ansali, G. Piat

Research output: Contribution to journalArticlepeer-review


The authors reviewed the records of 249 consecutive resections for NSC bronchogenic carcinoma. A second primary lung cancer (5 cases) occurred only among the 140 patients with resected T1-T2/N0 disease. In this category the cumulative survival rates were 59, 39 and 39% at 5, 10, 13 years, while the recurrence rates were 46, 60, 60% respectively and the risk for the development of new lung cancer was 4, 10, 40%. The time interval between first and second primary carcinoma was greater than 3 years in 4 of the 5 patients with metachronous lung cancer, while the mean interval was 6 years. In the majority of the cases, the new cancer was asymptomatic (60%), localized in the controlateral lung (80%), with a histologic cell type different from the previous primary (80%), and in stage I (80%). A second surgical management was possible in 3 of these cases. Long-term survival rates (5 years) following development or resection of the second primary lung cancer were 25-50% respectively.

Translated title of the contributionMultiple primary metachronous lung cancers
Original languageItalian
Pages (from-to)488-493
Number of pages6
Issue number9
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Surgery


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