Multisite Near Infrared Spectroscopy During Cardiopulmonary Bypass in Pediatric Patients

Zaccaria Ricci, Roberta Haiberger, Lorenzo Tofani, Stefano Romagnoli, Isabella Favia, Paola Cogo

Research output: Contribution to journalArticlepeer-review


Multisite near infrared spectroscopy (NIRS) monitoring during pediatric cardiopulmonary bypass (CPB) has not been extensively validated. Although it might be rational to explore regional tissue saturation at different body sites (namely brain, kidney, upper body, lower body), conflicting results are currently provided by experience in children. The aim of our study was to evaluate absolute values of multisite NIRS saturation during CPB in a cohort of infants undergoing pediatric cardiac surgery to describe average differences between cerebral, renal, upper body (arm), and lower body (thigh) regional saturation. Furthermore, the correlation between cerebral NIRS and cardiac index (CI) at CPB weaning was evaluated. Twenty-five infants were enrolled: their median weight, age, and body surface area were 3.9 (3.3-6) kg, 111 (47-203) days, and 0.24 (0.22-0.33) m2, respectively. Median Aristotle score was 8 (6-10), and vasoactive inotropic score at CPB weaning was 16 (14-25). A total of 17430 data points were recorded by each sensor: two-way ANOVA showed that time (P

Original languageEnglish
Pages (from-to)584-590
Number of pages7
JournalArtificial Organs
Issue number7
Publication statusPublished - Jul 1 2015


  • Cardiopulmonary bypass
  • Deep hypothermic circulatory arrest
  • Near-infrared spectroscopy
  • Pediatric cardiac surgery

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Bioengineering
  • Medicine (miscellaneous)


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