Multivessel coronary stenting: Predictors of early and late outcome

C. Briguori, T. Nishida, M. Adamian, C. Di Mario, J. Moses, A. Colombo

Research output: Contribution to journalArticlepeer-review


Background. At present, only few data are available on the early and late outcome following multivessel coronary stenting. Of note, in these studies, the left anterior descending (LAD) artery was treated in less than 40% of cases. These patients may not fully represent the population commonly referred for surgical revascularization. Methods. In-hospital and long-term (18 ± 4 months) events were evaluated in 272 consecutive patients who had multivessel stent implantation including the LAD artery in each case. All clinical, angiographic, and procedural variables were analyzed to identify the predictors of acute and long-term major adverse coronary events. Results. Eighteen patients (6.6%) had in-hospital major adverse coronary events (death 0.7%, coronary artery bypass grafting 0.4%, and myocardial infarction 6.3%). Acute and subacute stent thrombosis rates were 1.5 and 1.1%, respectively. At 18 ± 4 months, event-free survival was 71%. Target lesion revascularization was performed in 54 (20%) patients (42 coronary angioplasty and 12 coronary artery bypass grafting). The jeopardy score was the predictor of in-hospital major adverse coronary events (p = 0.016, odds ratio 1.34, 95% confidence interval 1.05-1.69), and diabetes mellitus was the predictor of long-term major adverse coronary events (p = 0.027, odds ratio 2.80, 95% confidence interval 1.12-6.96). Conclusions. Multivessel coronary stent implantation with treatment of the LAD artery in all instances is a safe procedure with low acute and long-term major adverse coronary events. The risk-benefit ratio must be assessed carefully for each patient, particularly taking into account the jeopardy score and the presence of diabetes mellitus.

Original languageEnglish
Pages (from-to)420-425
Number of pages6
JournalItalian Heart Journal
Issue number6
Publication statusPublished - 2000


  • Coronary angioplasty
  • Multivessel disease
  • Stent

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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