Muscle strength and bone in healthy women: Effect of age and gonadal status

Cristiana Cipriani, Elisabetta Romagnoli, Vincenzo Carnevale, Ida Raso, Addolorata Scarpiello, Maurizio Angelozzi, Andrea Tancredi, Stefania Russo, Federica de Lucia, Jessica Pepe, Salvatore Minisola

Research output: Contribution to journalArticlepeer-review


Objective: The aim of this work was to examine the effects of age and menopause on muscle strength and on the muscle-bone interaction. Design: One hundred ninety-four healthy women (mean age 49.8 ± 12.6 SD years) were assessed. Maximal Voluntary Contraction (MVC, Newton, N) by Hand Grip Dynamometer, bone mineral density at one third of the radius (R-BMD) by dual-energy X-ray absorptiometry (DXA) and phalangeal ultrasound by the DBM Sonic 1200 device were evaluated at the upper dominant limb. Ultrasonometric parameters considered were Amplitude-Dependent Speed of Sound (ADSoS) and Ultrasound Bone Profile Index (UBPI). Results: MVC significantly decreased with age (r2=-0.12, p2=0.015, p

Original languageEnglish
Pages (from-to)325-332
Number of pages8
Issue number3
Publication statusPublished - Jul 2012


  • Age
  • Bone
  • Menopause
  • Muscle
  • Strength

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism


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