Abstract
Human monocytes can differentiate into dendritic cells (DC) according to the nature of environmental signals. Pathogenic mycobacteria have been demonstrated interfere with this process to generate a not fully competent DC population. This mechanism is not common to non-pathogenic mycobacteria and could be correlated with bacterial virulence. However, it could represents a new mechanism of immune escape by persistent pathogens or a control mechanism of immune system to preserve the life of the organ against persistent infections.
Original language | English |
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Pages (from-to) | 115-117 |
Number of pages | 3 |
Journal | Immunology Letters |
Volume | 102 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 15 2006 |
Keywords
- Dendritic cells
- Monocyte differentiation
- Mycobacteria
ASJC Scopus subject areas
- Immunology
- Immunology and Allergy