Abstract
Human monocytes can differentiate into dendritic cells (DC) according to the nature of environmental signals. Pathogenic mycobacteria have been demonstrated interfere with this process to generate a not fully competent DC population. This mechanism is not common to non-pathogenic mycobacteria and could be correlated with bacterial virulence. However, it could represents a new mechanism of immune escape by persistent pathogens or a control mechanism of immune system to preserve the life of the organ against persistent infections.
| Original language | English |
|---|---|
| Pages (from-to) | 115-117 |
| Number of pages | 3 |
| Journal | Immunology Letters |
| Volume | 102 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 15 2006 |
Keywords
- Dendritic cells
- Monocyte differentiation
- Mycobacteria
ASJC Scopus subject areas
- Immunology
- Immunology and Allergy
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Martino, A., Sacchi, A., Colizzi, V., & Vendetti, S. (2006). Mycobacteria and dendritic cell differentiation: Escape or control of immunity. Immunology Letters, 102(1), 115-117. https://doi.org/10.1016/j.imlet.2005.06.016