Mycoplasma pneumoniae and Chlamydia pneumoniae infections in children with pneumonia

S. Esposito, F. Blasi, F. Bellini, L. Allegra, N. Principi

Research output: Contribution to journalArticle

Abstract

The most common clinical signs, host responses and radiographic patterns were studied in 203 Italian children hospitalized for community-acquired pneumonia in order to clarify the role of clinical and radiological characteristics in the diagnosis of Mycoplasma pneumoniae and/or Chlamydia pneumoniae infections. Antibody measurements in paired sera and polymerase chain reaction on nasopharyngeal aspirates were used to establish the diagnoses of acute. M. pneumoniae and C. pneumoniae infection, and the aetiologic data were correlated with the clinical, laboratory and radiographic data obtained on admission. No significant association was observed between evidence of M. pneumoniae and/or C. pneumoniae infection and periods of episode during the year, mean age of the study subjects, individual symptoms, physical findings or laboratory test results. Furthermore, no significant correlation was observed in relation to the radiological findings and M. pneumoniae and/or C. pneumoniae infection. This study shows that neither clinical findings nor laboratory parameters distinguished Mycoplasma pneumoniae and/or Chlamydia pneumoniae infection in children with pneumonia. Radiological findings also have a limited capacity to differentiate aetiologic agents. The priorities for future research include the development of rapid, easily accessible and cost-effective diagnostic tests useful for each episode of pneumonia in children.

Original languageEnglish
Pages (from-to)241-245
Number of pages5
JournalEuropean Respiratory Journal
Volume17
Issue number2
DOIs
Publication statusPublished - 2001

Fingerprint

Chlamydophila pneumoniae
Mycoplasma pneumoniae
Chlamydia Infections
Pneumonia
Hospitalized Child
Routine Diagnostic Tests
Costs and Cost Analysis
Polymerase Chain Reaction
Antibodies
Serum
Research

Keywords

  • Children
  • Chlamydia pneumoniae
  • Mycoplasma pneumoniae
  • Pneumonia

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Mycoplasma pneumoniae and Chlamydia pneumoniae infections in children with pneumonia. / Esposito, S.; Blasi, F.; Bellini, F.; Allegra, L.; Principi, N.

In: European Respiratory Journal, Vol. 17, No. 2, 2001, p. 241-245.

Research output: Contribution to journalArticle

Esposito, S. ; Blasi, F. ; Bellini, F. ; Allegra, L. ; Principi, N. / Mycoplasma pneumoniae and Chlamydia pneumoniae infections in children with pneumonia. In: European Respiratory Journal. 2001 ; Vol. 17, No. 2. pp. 241-245.
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