Mydriasis induced by sub-Tenon's ropivacaine injection in patients undergoing strabismus surgery

Gustavo Savino, Vittoria Perrotta, Daniela Colucci, Laura Balia, Maria Sammartino, Rossella Garra, Sergio Petroni, Alessandra Mastrocola, Emilio Balestrazzi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Purpose: To investigate the effects of sub-Tenon's capsule ropivacaine injection on pupillary diameter in strabismus surgery. Methods: A total of 16 patients were randomly assigned to 2 groups. The ropivacaine group (R) received sub-Tenon's ropivacaine 1% (2.5-3 mL) injections. In the control group (C), general anesthesia was induced and a saline solution (2.5-3 mL) was injected in the sub-Tenon's capsule. Pupillary diameter was measured at baseline and 2 and 5 minutes from the injections. The effects of the injections were expressed as a ratio of final (5 minutes) versus basal diameter. Results: A significant mydriasis occurred in the ropivacaine group when compared with the control group (Group R vs Group C ratio = 2.32, p <0.0001) or with unoperated fellow eye (R vs unoperated eye ratio = 2.29, p <0.0001). Conclusions: Ropivacaine in the sub-Tenon's capsule induces a mydriasis probably related to a pharmacological ciliary ganglion block.

Original languageEnglish
Pages (from-to)124-126
Number of pages3
JournalJournal of AAPOS
Volume14
Issue number2
DOIs
Publication statusPublished - Apr 2010

Fingerprint

Mydriasis
Strabismus
Tenon Capsule
Injections
Parasympathetic Ganglia
Control Groups
Sodium Chloride
General Anesthesia
ropivacaine
Pharmacology

ASJC Scopus subject areas

  • Ophthalmology
  • Pediatrics, Perinatology, and Child Health

Cite this

Savino, G., Perrotta, V., Colucci, D., Balia, L., Sammartino, M., Garra, R., ... Balestrazzi, E. (2010). Mydriasis induced by sub-Tenon's ropivacaine injection in patients undergoing strabismus surgery. Journal of AAPOS, 14(2), 124-126. https://doi.org/10.1016/j.jaapos.2009.11.022

Mydriasis induced by sub-Tenon's ropivacaine injection in patients undergoing strabismus surgery. / Savino, Gustavo; Perrotta, Vittoria; Colucci, Daniela; Balia, Laura; Sammartino, Maria; Garra, Rossella; Petroni, Sergio; Mastrocola, Alessandra; Balestrazzi, Emilio.

In: Journal of AAPOS, Vol. 14, No. 2, 04.2010, p. 124-126.

Research output: Contribution to journalArticle

Savino, G, Perrotta, V, Colucci, D, Balia, L, Sammartino, M, Garra, R, Petroni, S, Mastrocola, A & Balestrazzi, E 2010, 'Mydriasis induced by sub-Tenon's ropivacaine injection in patients undergoing strabismus surgery', Journal of AAPOS, vol. 14, no. 2, pp. 124-126. https://doi.org/10.1016/j.jaapos.2009.11.022
Savino, Gustavo ; Perrotta, Vittoria ; Colucci, Daniela ; Balia, Laura ; Sammartino, Maria ; Garra, Rossella ; Petroni, Sergio ; Mastrocola, Alessandra ; Balestrazzi, Emilio. / Mydriasis induced by sub-Tenon's ropivacaine injection in patients undergoing strabismus surgery. In: Journal of AAPOS. 2010 ; Vol. 14, No. 2. pp. 124-126.
@article{d9c5609f921f4b8ab9533cb709655716,
title = "Mydriasis induced by sub-Tenon's ropivacaine injection in patients undergoing strabismus surgery",
abstract = "Purpose: To investigate the effects of sub-Tenon's capsule ropivacaine injection on pupillary diameter in strabismus surgery. Methods: A total of 16 patients were randomly assigned to 2 groups. The ropivacaine group (R) received sub-Tenon's ropivacaine 1{\%} (2.5-3 mL) injections. In the control group (C), general anesthesia was induced and a saline solution (2.5-3 mL) was injected in the sub-Tenon's capsule. Pupillary diameter was measured at baseline and 2 and 5 minutes from the injections. The effects of the injections were expressed as a ratio of final (5 minutes) versus basal diameter. Results: A significant mydriasis occurred in the ropivacaine group when compared with the control group (Group R vs Group C ratio = 2.32, p <0.0001) or with unoperated fellow eye (R vs unoperated eye ratio = 2.29, p <0.0001). Conclusions: Ropivacaine in the sub-Tenon's capsule induces a mydriasis probably related to a pharmacological ciliary ganglion block.",
author = "Gustavo Savino and Vittoria Perrotta and Daniela Colucci and Laura Balia and Maria Sammartino and Rossella Garra and Sergio Petroni and Alessandra Mastrocola and Emilio Balestrazzi",
year = "2010",
month = "4",
doi = "10.1016/j.jaapos.2009.11.022",
language = "English",
volume = "14",
pages = "124--126",
journal = "Journal of AAPOS",
issn = "1091-8531",
publisher = "Mosby Inc.",
number = "2",

}

TY - JOUR

T1 - Mydriasis induced by sub-Tenon's ropivacaine injection in patients undergoing strabismus surgery

AU - Savino, Gustavo

AU - Perrotta, Vittoria

AU - Colucci, Daniela

AU - Balia, Laura

AU - Sammartino, Maria

AU - Garra, Rossella

AU - Petroni, Sergio

AU - Mastrocola, Alessandra

AU - Balestrazzi, Emilio

PY - 2010/4

Y1 - 2010/4

N2 - Purpose: To investigate the effects of sub-Tenon's capsule ropivacaine injection on pupillary diameter in strabismus surgery. Methods: A total of 16 patients were randomly assigned to 2 groups. The ropivacaine group (R) received sub-Tenon's ropivacaine 1% (2.5-3 mL) injections. In the control group (C), general anesthesia was induced and a saline solution (2.5-3 mL) was injected in the sub-Tenon's capsule. Pupillary diameter was measured at baseline and 2 and 5 minutes from the injections. The effects of the injections were expressed as a ratio of final (5 minutes) versus basal diameter. Results: A significant mydriasis occurred in the ropivacaine group when compared with the control group (Group R vs Group C ratio = 2.32, p <0.0001) or with unoperated fellow eye (R vs unoperated eye ratio = 2.29, p <0.0001). Conclusions: Ropivacaine in the sub-Tenon's capsule induces a mydriasis probably related to a pharmacological ciliary ganglion block.

AB - Purpose: To investigate the effects of sub-Tenon's capsule ropivacaine injection on pupillary diameter in strabismus surgery. Methods: A total of 16 patients were randomly assigned to 2 groups. The ropivacaine group (R) received sub-Tenon's ropivacaine 1% (2.5-3 mL) injections. In the control group (C), general anesthesia was induced and a saline solution (2.5-3 mL) was injected in the sub-Tenon's capsule. Pupillary diameter was measured at baseline and 2 and 5 minutes from the injections. The effects of the injections were expressed as a ratio of final (5 minutes) versus basal diameter. Results: A significant mydriasis occurred in the ropivacaine group when compared with the control group (Group R vs Group C ratio = 2.32, p <0.0001) or with unoperated fellow eye (R vs unoperated eye ratio = 2.29, p <0.0001). Conclusions: Ropivacaine in the sub-Tenon's capsule induces a mydriasis probably related to a pharmacological ciliary ganglion block.

UR - http://www.scopus.com/inward/record.url?scp=77951667543&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951667543&partnerID=8YFLogxK

U2 - 10.1016/j.jaapos.2009.11.022

DO - 10.1016/j.jaapos.2009.11.022

M3 - Article

VL - 14

SP - 124

EP - 126

JO - Journal of AAPOS

JF - Journal of AAPOS

SN - 1091-8531

IS - 2

ER -