Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy

M. Gomez-Lira, M. G. Marzari, G. Uziel, Pf Pignatti, N. Rizzuto, A. Salviati

Research output: Contribution to journalArticlepeer-review

Abstract

We describe four novel sequence variants in the Myelin Oligodendrocyte Glycoprotein (MOG) gene. A total of six sequence variants of the MOG gene were identified in eleven out of 44 ALD patients investigated: G15A, CTC repeat in exon 1, Val142Leu, Val145Ile, 551+68A→G and 551+77C→T. Screening studies demonstrated that all these polymorphisms are present in 50 unaffected control male individuals of the same population and in the different phenotypes of ALD patients, indicating that they do not contribute to phenotype variability in ALD Copyright (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)245-247
Number of pages3
JournalJournal of Neuroimmunology
Volume111
Issue number1-2
DOIs
Publication statusPublished - Nov 1 2000

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Clinical Neurology
  • Neurology

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