Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy

M. Gomez-Lira, M. G. Marzari, G. Uziel, Pf Pignatti, N. Rizzuto, A. Salviati

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We describe four novel sequence variants in the Myelin Oligodendrocyte Glycoprotein (MOG) gene. A total of six sequence variants of the MOG gene were identified in eleven out of 44 ALD patients investigated: G15A, CTC repeat in exon 1, Val142Leu, Val145Ile, 551+68A→G and 551+77C→T. Screening studies demonstrated that all these polymorphisms are present in 50 unaffected control male individuals of the same population and in the different phenotypes of ALD patients, indicating that they do not contribute to phenotype variability in ALD Copyright (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)245-247
Number of pages3
JournalJournal of Neuroimmunology
Volume111
Issue number1-2
DOIs
Publication statusPublished - Nov 1 2000

Fingerprint

Myelin-Oligodendrocyte Glycoprotein
Adrenoleukodystrophy
Phenotype
Genes
Exons
Population

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Clinical Neurology
  • Neurology

Cite this

Gomez-Lira, M., Marzari, M. G., Uziel, G., Pignatti, P., Rizzuto, N., & Salviati, A. (2000). Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy. Journal of Neuroimmunology, 111(1-2), 245-247. https://doi.org/10.1016/S0165-5728(00)00367-2

Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy. / Gomez-Lira, M.; Marzari, M. G.; Uziel, G.; Pignatti, Pf; Rizzuto, N.; Salviati, A.

In: Journal of Neuroimmunology, Vol. 111, No. 1-2, 01.11.2000, p. 245-247.

Research output: Contribution to journalArticle

Gomez-Lira, M, Marzari, MG, Uziel, G, Pignatti, P, Rizzuto, N & Salviati, A 2000, 'Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy', Journal of Neuroimmunology, vol. 111, no. 1-2, pp. 245-247. https://doi.org/10.1016/S0165-5728(00)00367-2
Gomez-Lira M, Marzari MG, Uziel G, Pignatti P, Rizzuto N, Salviati A. Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy. Journal of Neuroimmunology. 2000 Nov 1;111(1-2):245-247. https://doi.org/10.1016/S0165-5728(00)00367-2
Gomez-Lira, M. ; Marzari, M. G. ; Uziel, G. ; Pignatti, Pf ; Rizzuto, N. ; Salviati, A. / Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy. In: Journal of Neuroimmunology. 2000 ; Vol. 111, No. 1-2. pp. 245-247.
@article{aef0487b595048e68281313e1003d634,
title = "Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy",
abstract = "We describe four novel sequence variants in the Myelin Oligodendrocyte Glycoprotein (MOG) gene. A total of six sequence variants of the MOG gene were identified in eleven out of 44 ALD patients investigated: G15A, CTC repeat in exon 1, Val142Leu, Val145Ile, 551+68A→G and 551+77C→T. Screening studies demonstrated that all these polymorphisms are present in 50 unaffected control male individuals of the same population and in the different phenotypes of ALD patients, indicating that they do not contribute to phenotype variability in ALD Copyright (C) 2000 Elsevier Science B.V.",
author = "M. Gomez-Lira and Marzari, {M. G.} and G. Uziel and Pf Pignatti and N. Rizzuto and A. Salviati",
year = "2000",
month = "11",
day = "1",
doi = "10.1016/S0165-5728(00)00367-2",
language = "English",
volume = "111",
pages = "245--247",
journal = "Journal of Neuroimmunology",
issn = "0165-5728",
publisher = "Elsevier Science B.V.",
number = "1-2",

}

TY - JOUR

T1 - Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy

AU - Gomez-Lira, M.

AU - Marzari, M. G.

AU - Uziel, G.

AU - Pignatti, Pf

AU - Rizzuto, N.

AU - Salviati, A.

PY - 2000/11/1

Y1 - 2000/11/1

N2 - We describe four novel sequence variants in the Myelin Oligodendrocyte Glycoprotein (MOG) gene. A total of six sequence variants of the MOG gene were identified in eleven out of 44 ALD patients investigated: G15A, CTC repeat in exon 1, Val142Leu, Val145Ile, 551+68A→G and 551+77C→T. Screening studies demonstrated that all these polymorphisms are present in 50 unaffected control male individuals of the same population and in the different phenotypes of ALD patients, indicating that they do not contribute to phenotype variability in ALD Copyright (C) 2000 Elsevier Science B.V.

AB - We describe four novel sequence variants in the Myelin Oligodendrocyte Glycoprotein (MOG) gene. A total of six sequence variants of the MOG gene were identified in eleven out of 44 ALD patients investigated: G15A, CTC repeat in exon 1, Val142Leu, Val145Ile, 551+68A→G and 551+77C→T. Screening studies demonstrated that all these polymorphisms are present in 50 unaffected control male individuals of the same population and in the different phenotypes of ALD patients, indicating that they do not contribute to phenotype variability in ALD Copyright (C) 2000 Elsevier Science B.V.

UR - http://www.scopus.com/inward/record.url?scp=0034332952&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034332952&partnerID=8YFLogxK

U2 - 10.1016/S0165-5728(00)00367-2

DO - 10.1016/S0165-5728(00)00367-2

M3 - Article

VL - 111

SP - 245

EP - 247

JO - Journal of Neuroimmunology

JF - Journal of Neuroimmunology

SN - 0165-5728

IS - 1-2

ER -