Abstract
We describe four novel sequence variants in the Myelin Oligodendrocyte Glycoprotein (MOG) gene. A total of six sequence variants of the MOG gene were identified in eleven out of 44 ALD patients investigated: G15A, CTC repeat in exon 1, Val142Leu, Val145Ile, 551+68A→G and 551+77C→T. Screening studies demonstrated that all these polymorphisms are present in 50 unaffected control male individuals of the same population and in the different phenotypes of ALD patients, indicating that they do not contribute to phenotype variability in ALD Copyright (C) 2000 Elsevier Science B.V.
| Original language | English |
|---|---|
| Pages (from-to) | 245-247 |
| Number of pages | 3 |
| Journal | Journal of Neuroimmunology |
| Volume | 111 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - Nov 1 2000 |
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ASJC Scopus subject areas
- Immunology
- Immunology and Allergy
- Clinical Neurology
- Neurology
Cite this
Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy. / Gomez-Lira, M.; Marzari, M. G.; Uziel, G.; Pignatti, Pf; Rizzuto, N.; Salviati, A.
In: Journal of Neuroimmunology, Vol. 111, No. 1-2, 01.11.2000, p. 245-247.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy
AU - Gomez-Lira, M.
AU - Marzari, M. G.
AU - Uziel, G.
AU - Pignatti, Pf
AU - Rizzuto, N.
AU - Salviati, A.
PY - 2000/11/1
Y1 - 2000/11/1
N2 - We describe four novel sequence variants in the Myelin Oligodendrocyte Glycoprotein (MOG) gene. A total of six sequence variants of the MOG gene were identified in eleven out of 44 ALD patients investigated: G15A, CTC repeat in exon 1, Val142Leu, Val145Ile, 551+68A→G and 551+77C→T. Screening studies demonstrated that all these polymorphisms are present in 50 unaffected control male individuals of the same population and in the different phenotypes of ALD patients, indicating that they do not contribute to phenotype variability in ALD Copyright (C) 2000 Elsevier Science B.V.
AB - We describe four novel sequence variants in the Myelin Oligodendrocyte Glycoprotein (MOG) gene. A total of six sequence variants of the MOG gene were identified in eleven out of 44 ALD patients investigated: G15A, CTC repeat in exon 1, Val142Leu, Val145Ile, 551+68A→G and 551+77C→T. Screening studies demonstrated that all these polymorphisms are present in 50 unaffected control male individuals of the same population and in the different phenotypes of ALD patients, indicating that they do not contribute to phenotype variability in ALD Copyright (C) 2000 Elsevier Science B.V.
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UR - http://www.scopus.com/inward/citedby.url?scp=0034332952&partnerID=8YFLogxK
U2 - 10.1016/S0165-5728(00)00367-2
DO - 10.1016/S0165-5728(00)00367-2
M3 - Article
VL - 111
SP - 245
EP - 247
JO - Journal of Neuroimmunology
JF - Journal of Neuroimmunology
SN - 0165-5728
IS - 1-2
ER -