Abstract
In this review, we debate the evidence for abnormal white matter microstructure and myelination in bipolar disorder, as mainly detected by diffusion tensor imaging (DTI) studies. The effects of mood stabilizers on white matter are discussed, based on available findings from human and animal studies. Last, perspectives in this field of research are also drawn.
| Original language | English |
|---|---|
| Pages (from-to) | 2632-2636 |
| Number of pages | 5 |
| Journal | Current Pharmaceutical Design |
| Volume | 15 |
| Issue number | 22 |
| DOIs | |
| Publication status | Published - 2009 |
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Keywords
- Amygdala
- Corpus callosum
- Diffusion imaging
- Hippocampus
- Lithium
- Prefrontal cortex
- Valproate
- White matter
ASJC Scopus subject areas
- Drug Discovery
- Pharmacology
Cite this
Myelination in bipolar patients and the effects of mood stabilizers on brain anatomy. / Brambilla, Paolo; Bellani, Marcella; Yeh, Ping Hong; Soares, Jair C.
In: Current Pharmaceutical Design, Vol. 15, No. 22, 2009, p. 2632-2636.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Myelination in bipolar patients and the effects of mood stabilizers on brain anatomy
AU - Brambilla, Paolo
AU - Bellani, Marcella
AU - Yeh, Ping Hong
AU - Soares, Jair C.
PY - 2009
Y1 - 2009
N2 - In this review, we debate the evidence for abnormal white matter microstructure and myelination in bipolar disorder, as mainly detected by diffusion tensor imaging (DTI) studies. The effects of mood stabilizers on white matter are discussed, based on available findings from human and animal studies. Last, perspectives in this field of research are also drawn.
AB - In this review, we debate the evidence for abnormal white matter microstructure and myelination in bipolar disorder, as mainly detected by diffusion tensor imaging (DTI) studies. The effects of mood stabilizers on white matter are discussed, based on available findings from human and animal studies. Last, perspectives in this field of research are also drawn.
KW - Amygdala
KW - Corpus callosum
KW - Diffusion imaging
KW - Hippocampus
KW - Lithium
KW - Prefrontal cortex
KW - Valproate
KW - White matter
UR - http://www.scopus.com/inward/record.url?scp=69249123346&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=69249123346&partnerID=8YFLogxK
U2 - 10.2174/138161209788957519
DO - 10.2174/138161209788957519
M3 - Article
C2 - 19689333
AN - SCOPUS:69249123346
VL - 15
SP - 2632
EP - 2636
JO - Current Pharmaceutical Design
JF - Current Pharmaceutical Design
SN - 1381-6128
IS - 22
ER -