Abstract
In this review, we debate the evidence for abnormal white matter microstructure and myelination in bipolar disorder, as mainly detected by diffusion tensor imaging (DTI) studies. The effects of mood stabilizers on white matter are discussed, based on available findings from human and animal studies. Last, perspectives in this field of research are also drawn.
| Original language | English |
|---|---|
| Pages (from-to) | 2632-2636 |
| Number of pages | 5 |
| Journal | Current Pharmaceutical Design |
| Volume | 15 |
| Issue number | 22 |
| DOIs | |
| Publication status | Published - 2009 |
Keywords
- Amygdala
- Corpus callosum
- Diffusion imaging
- Hippocampus
- Lithium
- Prefrontal cortex
- Valproate
- White matter
ASJC Scopus subject areas
- Drug Discovery
- Pharmacology
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Brambilla, P., Bellani, M., Yeh, P. H., & Soares, J. C. (2009). Myelination in bipolar patients and the effects of mood stabilizers on brain anatomy. Current Pharmaceutical Design, 15(22), 2632-2636. https://doi.org/10.2174/138161209788957519