Myelination in bipolar patients and the effects of mood stabilizers on brain anatomy

Paolo Brambilla; Marcella Bellani; Ping Hong Yeh; Jair C. Soares

doi:10.2174/138161209788957519

Myelination in bipolar patients and the effects of mood stabilizers on brain anatomy

Paolo Brambilla, Marcella Bellani, Ping Hong Yeh, Jair C. Soares

Istituto "Eugenio Medea" - Associazione La Nostra Famiglia

Research output: Contribution to journal › Article › peer-review

Abstract

In this review, we debate the evidence for abnormal white matter microstructure and myelination in bipolar disorder, as mainly detected by diffusion tensor imaging (DTI) studies. The effects of mood stabilizers on white matter are discussed, based on available findings from human and animal studies. Last, perspectives in this field of research are also drawn.

Original language	English
Pages (from-to)	2632-2636
Number of pages	5
Journal	Current Pharmaceutical Design
Volume	15
Issue number	22
DOIs	https://doi.org/10.2174/138161209788957519
Publication status	Published - 2009

Keywords

Amygdala
Corpus callosum
Diffusion imaging
Hippocampus
Lithium
Prefrontal cortex
Valproate
White matter

ASJC Scopus subject areas

Drug Discovery
Pharmacology

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10.2174/138161209788957519

Cite this

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abstract = "In this review, we debate the evidence for abnormal white matter microstructure and myelination in bipolar disorder, as mainly detected by diffusion tensor imaging (DTI) studies. The effects of mood stabilizers on white matter are discussed, based on available findings from human and animal studies. Last, perspectives in this field of research are also drawn.",

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Myelination in bipolar patients and the effects of mood stabilizers on brain anatomy

Abstract

Keywords

ASJC Scopus subject areas

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