Myelofibrosis with myeloid metaplasia following essential thrombocythaemia

Nicola Lucio Liberato, Giovanni Barosi, Attilia Costa, Paola D’Elia, Piero Boccaccio

Research output: Contribution to journalArticlepeer-review


We report a male patient in whom a diagnosis of essential thrombocythaemia was made at the age of 25. The clinical course was characterised by recurrent thrombotic episodes during the first few years of the disease, followed by a relatively benign course. He was treated with32P, nitrogen mustard and plateletpheresis. A transformation into myelofibrosis with myeloid metaplasia was revealed 20 years after ET diagnosis. The length of the disease and the32P therapy are discussed as factors favouring this metamorphosis.

Original languageEnglish
Pages (from-to)150-153
Number of pages4
JournalActa Haematologica
Issue number3
Publication statusPublished - 1989


  • Essential thrombocythaemia
  • Myelofibrosis with myeloid metaplasia

ASJC Scopus subject areas

  • Hematology


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