Abstract
We report a male patient in whom a diagnosis of essential thrombocythaemia was made at the age of 25. The clinical course was characterised by recurrent thrombotic episodes during the first few years of the disease, followed by a relatively benign course. He was treated with32P, nitrogen mustard and plateletpheresis. A transformation into myelofibrosis with myeloid metaplasia was revealed 20 years after ET diagnosis. The length of the disease and the32P therapy are discussed as factors favouring this metamorphosis.
Original language | English |
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Pages (from-to) | 150-153 |
Number of pages | 4 |
Journal | Acta Haematologica |
Volume | 82 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1989 |
Keywords
- Essential thrombocythaemia
- Myelofibrosis with myeloid metaplasia
ASJC Scopus subject areas
- Hematology