TY - JOUR
T1 - Myeloid sarcoma
T2 - Extramedullary manifestation of myeloid disorders
AU - Campidelli, Cristina
AU - Agostinelli, Claudio
AU - Stitson, Richard
AU - Pileri, Stefano A.
PY - 2009/9
Y1 - 2009/9
N2 - Myeloid sarcoma (MS), also termed extramedullary acute myeloid leukemia, extramedullary myeloid tumor, and granulocytic sarcoma or chloroma, is a rare manifestation that is characterized by the occurrence of 1 or more tumor myeloid masses occurring at an extramedullary site. The wide spectrum of this disorder and the conditions that it overlaps diagnostically were well reflected in the 25 cases submitted to the Society for Hematopathology/European Association for Haematopathology Workshop held in Indianapolis, IN, in November 2007. This review, on the one hand, focuses on the definition and most recent achievements on the pathobiology of MS, and on the other, also in the light of the revised World Health Organization classification, summarizes the main features of a representative series of this condition aiming to provide readers a useful document for daily practice.
AB - Myeloid sarcoma (MS), also termed extramedullary acute myeloid leukemia, extramedullary myeloid tumor, and granulocytic sarcoma or chloroma, is a rare manifestation that is characterized by the occurrence of 1 or more tumor myeloid masses occurring at an extramedullary site. The wide spectrum of this disorder and the conditions that it overlaps diagnostically were well reflected in the 25 cases submitted to the Society for Hematopathology/European Association for Haematopathology Workshop held in Indianapolis, IN, in November 2007. This review, on the one hand, focuses on the definition and most recent achievements on the pathobiology of MS, and on the other, also in the light of the revised World Health Organization classification, summarizes the main features of a representative series of this condition aiming to provide readers a useful document for daily practice.
KW - Cytogenetics
KW - FISH
KW - Fluorescence in situ hybridization
KW - Molecular biology
KW - Myeloid sarcoma
KW - Phenotype
UR - http://www.scopus.com/inward/record.url?scp=69849101382&partnerID=8YFLogxK
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U2 - 10.1309/AJCP1ZA7HYZKAZHS
DO - 10.1309/AJCP1ZA7HYZKAZHS
M3 - Article
C2 - 19687319
AN - SCOPUS:69849101382
VL - 132
SP - 426
EP - 437
JO - American Journal of Clinical Pathology
JF - American Journal of Clinical Pathology
SN - 0002-9173
IS - 3
ER -