Delayed enhancement miocardico con singola dose (0.1 mmol/kg) di gadobenato dimeglumina: risoluzione di contrasto rispetto al sangue ventricolare ed al miocardio sano

Translated title of the contribution: Myocardial delayed enhancement using a single dose (0.1 mmol/kg) of gadobenate dimeglumine: Contrast resolution versus intraventricular blood and viable myocardium

G. D E Papini, S. Tritella, F. Secchi, A. Aliprandi, G. Di Leo, F. Sardanelli

Research output: Contribution to journalArticle

Abstract

Purpose: This study was done to estimate delayed enhancement (DE) contrast resolution of infarcted myocardium (IM) relative to intraventricular blood (IB) and viable myocardium (VM) using gadobenate dimeglumine (Gd-BOPTA). Materials and methods: After approval from the Ethics Committee, we retrospectively evaluated 21 consecutive patients (61±10 years) with a healed myocardial infarction who underwent 1.5-T magnetic resonance (MR) imaging using an inversion-recovery-prepared turbo gradient-echo sequence 10 minutes after injection of 0.1 mmol/kg of Gd-BOPTA. Signal intensity (SI) was measured in arbitrary units (au) for IM, IB, VM, and outside the patient. Contrast-to-noise ratio (CNR) was calculated for IM to IB and IM to VM. Seven consecutive patients (59±6 years) with a healed myocardial infarction studied with similar technique but with 0.1 mmol/kg of gadoterate meglumine (Gd-DOTA) served as the control group. The Mann-Whitney U test was used to compare groups. Results: Mean SI of IM was 44±16 au for Gd-BOPTA and 20±6 au for Gd-DOTA (p

Original languageItalian
Pages (from-to)693-701
Number of pages9
JournalRadiologia Medica
Volume115
Issue number5
DOIs
Publication statusPublished - Aug 2010

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Myocardium
Myocardial Infarction
Ethics Committees
gadobenic acid
Nonparametric Statistics
Noise
Magnetic Resonance Imaging
Control Groups
Injections

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

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title = "Delayed enhancement miocardico con singola dose (0.1 mmol/kg) di gadobenato dimeglumina: risoluzione di contrasto rispetto al sangue ventricolare ed al miocardio sano",
abstract = "Purpose: This study was done to estimate delayed enhancement (DE) contrast resolution of infarcted myocardium (IM) relative to intraventricular blood (IB) and viable myocardium (VM) using gadobenate dimeglumine (Gd-BOPTA). Materials and methods: After approval from the Ethics Committee, we retrospectively evaluated 21 consecutive patients (61±10 years) with a healed myocardial infarction who underwent 1.5-T magnetic resonance (MR) imaging using an inversion-recovery-prepared turbo gradient-echo sequence 10 minutes after injection of 0.1 mmol/kg of Gd-BOPTA. Signal intensity (SI) was measured in arbitrary units (au) for IM, IB, VM, and outside the patient. Contrast-to-noise ratio (CNR) was calculated for IM to IB and IM to VM. Seven consecutive patients (59±6 years) with a healed myocardial infarction studied with similar technique but with 0.1 mmol/kg of gadoterate meglumine (Gd-DOTA) served as the control group. The Mann-Whitney U test was used to compare groups. Results: Mean SI of IM was 44±16 au for Gd-BOPTA and 20±6 au for Gd-DOTA (p",
keywords = "Cardiac magnetic resonance (CMR), Delayed enhancement (DE), Gadobenate dimeglumine (Gd-BOPTA), Gadoterate meglumine (Gd-DOTA), Myocardium",
author = "Papini, {G. D E} and S. Tritella and F. Secchi and A. Aliprandi and {Di Leo}, G. and F. Sardanelli",
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pages = "693--701",
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T1 - Delayed enhancement miocardico con singola dose (0.1 mmol/kg) di gadobenato dimeglumina

T2 - risoluzione di contrasto rispetto al sangue ventricolare ed al miocardio sano

AU - Papini, G. D E

AU - Tritella, S.

AU - Secchi, F.

AU - Aliprandi, A.

AU - Di Leo, G.

AU - Sardanelli, F.

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N2 - Purpose: This study was done to estimate delayed enhancement (DE) contrast resolution of infarcted myocardium (IM) relative to intraventricular blood (IB) and viable myocardium (VM) using gadobenate dimeglumine (Gd-BOPTA). Materials and methods: After approval from the Ethics Committee, we retrospectively evaluated 21 consecutive patients (61±10 years) with a healed myocardial infarction who underwent 1.5-T magnetic resonance (MR) imaging using an inversion-recovery-prepared turbo gradient-echo sequence 10 minutes after injection of 0.1 mmol/kg of Gd-BOPTA. Signal intensity (SI) was measured in arbitrary units (au) for IM, IB, VM, and outside the patient. Contrast-to-noise ratio (CNR) was calculated for IM to IB and IM to VM. Seven consecutive patients (59±6 years) with a healed myocardial infarction studied with similar technique but with 0.1 mmol/kg of gadoterate meglumine (Gd-DOTA) served as the control group. The Mann-Whitney U test was used to compare groups. Results: Mean SI of IM was 44±16 au for Gd-BOPTA and 20±6 au for Gd-DOTA (p

AB - Purpose: This study was done to estimate delayed enhancement (DE) contrast resolution of infarcted myocardium (IM) relative to intraventricular blood (IB) and viable myocardium (VM) using gadobenate dimeglumine (Gd-BOPTA). Materials and methods: After approval from the Ethics Committee, we retrospectively evaluated 21 consecutive patients (61±10 years) with a healed myocardial infarction who underwent 1.5-T magnetic resonance (MR) imaging using an inversion-recovery-prepared turbo gradient-echo sequence 10 minutes after injection of 0.1 mmol/kg of Gd-BOPTA. Signal intensity (SI) was measured in arbitrary units (au) for IM, IB, VM, and outside the patient. Contrast-to-noise ratio (CNR) was calculated for IM to IB and IM to VM. Seven consecutive patients (59±6 years) with a healed myocardial infarction studied with similar technique but with 0.1 mmol/kg of gadoterate meglumine (Gd-DOTA) served as the control group. The Mann-Whitney U test was used to compare groups. Results: Mean SI of IM was 44±16 au for Gd-BOPTA and 20±6 au for Gd-DOTA (p

KW - Cardiac magnetic resonance (CMR)

KW - Delayed enhancement (DE)

KW - Gadobenate dimeglumine (Gd-BOPTA)

KW - Gadoterate meglumine (Gd-DOTA)

KW - Myocardium

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