Abstract
We describe the first case of acute cardiac injury directly linked to myocardial localization of severe acute respiratory syndrome coronavirus (SARS-CoV-2) in a 69-year-old patient with flu-like symptoms rapidly degenerating into respiratory distress, hypotension, and cardiogenic shock. The patient was successfully treated with venous-arterial extracorporeal membrane oxygenation (ECMO) and mechanical ventilation. Cardiac function fully recovered in 5 days and ECMO was removed. Endomyocardial biopsy demonstrated low-grade myocardial inflammation and viral particles in the myocardium suggesting either a viraemic phase or, alternatively, infected macrophage migration from the lung.
Original language | English |
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Journal | European Journal of Heart Failure |
DOIs | |
Publication status | Accepted/In press - Jan 1 2020 |
Keywords
- Cardiac injury
- Cardiogenic shock
- Coronavirus
- Extracorporeal membrane oxygenation
- Myocardial inflammation
- SARS-CoV-2
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine