Myocardial localization of coronavirus in COVID-19 cardiogenic shock

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We describe the first case of acute cardiac injury directly linked to myocardial localization of severe acute respiratory syndrome coronavirus (SARS-CoV-2) in a 69-year-old patient with flu-like symptoms rapidly degenerating into respiratory distress, hypotension, and cardiogenic shock. The patient was successfully treated with venous-arterial extracorporeal membrane oxygenation (ECMO) and mechanical ventilation. Cardiac function fully recovered in 5 days and ECMO was removed. Endomyocardial biopsy demonstrated low-grade myocardial inflammation and viral particles in the myocardium suggesting either a viraemic phase or, alternatively, infected macrophage migration from the lung.

Original languageEnglish
JournalEuropean Journal of Heart Failure
Publication statusAccepted/In press - Jan 1 2020


  • Cardiac injury
  • Cardiogenic shock
  • Coronavirus
  • Extracorporeal membrane oxygenation
  • Myocardial inflammation
  • SARS-CoV-2

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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