Myocardial reconstruction in ischaemic cardiomyopathy

Serenella Castelvecchio, Omar Antonio Pappalardo, Lorenzo Menicanti

Research output: Contribution to journalReview articlepeer-review


An increase in left ventricular volume after a myocardial infarction is a key component of the adverse remodelling process leading to chamber dysfunction, heart failure and an unfavourable outcome. Hence, the therapeutic strategies have been designed to reverse the remodelling process by medical therapy, devices or surgical strategies. Surgical ventricular reconstruction primarily combined with myocardial revascularization has been introduced as an optional intervention aimed to reduce the left ventricle through resection of the scar tissue and is recommended in selected patients with predominant heart failure symptoms, and with myocardial scarring and moderate left ventricular remodelling. This review outlines the rationale and the technique for reconstructing the left ventricle and the possible indications for using that technique, based on experiences from the centre with the largest international experience. The major contributions in the literature are briefly discussed .

Original languageEnglish
Article numberezy367
Pages (from-to)I49-56
JournalEuropean Journal of Cardio-thoracic Surgery
Publication statusPublished - Jun 1 2019


  • Heart failure
  • Left ventricular remodeling
  • Surgical ventricular reconstruction

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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