Stato di male mioclonico indotto da gabapentin in un paziente con Benign Adult Familial Myoclonic Epilepsy (BAFME)

We describe clinical and electrophysiological findings of a 57 years old patient who experienced life-threatening myoclonic status after administration of gabapentin. The myoclonic status did not respond to benzodiazepines, but resolved after discontinuing gabapentin. While of obtaining a family medical history, we determined that the patient belonged to a previously reported kindred segregating Benign Adult Familial Myoclonic Epilepsy (BAFME), and electrophysiological investigations (video-EEG, back-averaging, somatosensory evoked potentials and long-loop reflex I) confirmed the diagnosis of a cortical tremor.