Myoclonus in corticobasal degeneration

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Five patients with unilateral myoclonus and a clinical diagnosis of corticobasal degeneration (CBD) were studied. All patients showed enhanced long-loop responses in their myoclonic arms without enlarged somatosensory potentials. The cortical relay time of the long-loop responses was studied in three patients, in two of whom it was <2 ms, even in the nonmyoclonic arm. Myoclonus in CBD is probably related to an enhanced long-loop reflex whose pathway is unlikely to be the same as that in classic cortical reflex myoclonus.

Original languageEnglish
Pages (from-to)598-603
Number of pages6
JournalMovement Disorders
Issue number4
Publication statusPublished - 1997


  • Corticobasal degeneration
  • Long-loop responses
  • Myoclonus
  • Somatosensory evoked potential

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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