Abstract
The case of a 69-year-old woman who developed muscle weakness on chronic amiodarone treatment is reported. Muscle biopsy showed vacuolar alterations and a marked accumulation of amiodarone and of its metabolite desethylamiodarone was found in the muscle sample despite normal blood levels. Amiodarone-induced morphological alterations of the muscle may be related to the actual tissue concentration rather than to the blood level.
Original language | English |
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Pages (from-to) | 603-608 |
Number of pages | 6 |
Journal | Italian Journal of Neurological Sciences |
Volume | 8 |
Issue number | 6 |
DOIs | |
Publication status | Published - Dec 1987 |
Keywords
- Amiodarone
- side effects
ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology