Myopathy during amiodarone treatment: a case report

F. Carella, E. Riva, L. Morandi, E. Cappiello, A. Mangoni

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The case of a 69-year-old woman who developed muscle weakness on chronic amiodarone treatment is reported. Muscle biopsy showed vacuolar alterations and a marked accumulation of amiodarone and of its metabolite desethylamiodarone was found in the muscle sample despite normal blood levels. Amiodarone-induced morphological alterations of the muscle may be related to the actual tissue concentration rather than to the blood level.

Original languageEnglish
Pages (from-to)603-608
Number of pages6
JournalItalian Journal of Neurological Sciences
Volume8
Issue number6
DOIs
Publication statusPublished - Dec 1987

Fingerprint

Amiodarone
Muscular Diseases
Muscles
Muscle Weakness
Therapeutics
Biopsy

Keywords

  • Amiodarone
  • side effects

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Carella, F., Riva, E., Morandi, L., Cappiello, E., & Mangoni, A. (1987). Myopathy during amiodarone treatment: a case report. Italian Journal of Neurological Sciences, 8(6), 603-608. https://doi.org/10.1007/BF02333668

Myopathy during amiodarone treatment : a case report. / Carella, F.; Riva, E.; Morandi, L.; Cappiello, E.; Mangoni, A.

In: Italian Journal of Neurological Sciences, Vol. 8, No. 6, 12.1987, p. 603-608.

Research output: Contribution to journalArticle

Carella, F, Riva, E, Morandi, L, Cappiello, E & Mangoni, A 1987, 'Myopathy during amiodarone treatment: a case report', Italian Journal of Neurological Sciences, vol. 8, no. 6, pp. 603-608. https://doi.org/10.1007/BF02333668
Carella, F. ; Riva, E. ; Morandi, L. ; Cappiello, E. ; Mangoni, A. / Myopathy during amiodarone treatment : a case report. In: Italian Journal of Neurological Sciences. 1987 ; Vol. 8, No. 6. pp. 603-608.
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