Abstract
The case of a 69-year-old woman who developed muscle weakness on chronic amiodarone treatment is reported. Muscle biopsy showed vacuolar alterations and a marked accumulation of amiodarone and of its metabolite desethylamiodarone was found in the muscle sample despite normal blood levels. Amiodarone-induced morphological alterations of the muscle may be related to the actual tissue concentration rather than to the blood level.
| Original language | English |
|---|---|
| Pages (from-to) | 603-608 |
| Number of pages | 6 |
| Journal | Italian Journal of Neurological Sciences |
| Volume | 8 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Dec 1987 |
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Keywords
- Amiodarone
- side effects
ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology
Cite this
Myopathy during amiodarone treatment : a case report. / Carella, F.; Riva, E.; Morandi, L.; Cappiello, E.; Mangoni, A.
In: Italian Journal of Neurological Sciences, Vol. 8, No. 6, 12.1987, p. 603-608.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Myopathy during amiodarone treatment
T2 - a case report
AU - Carella, F.
AU - Riva, E.
AU - Morandi, L.
AU - Cappiello, E.
AU - Mangoni, A.
PY - 1987/12
Y1 - 1987/12
N2 - The case of a 69-year-old woman who developed muscle weakness on chronic amiodarone treatment is reported. Muscle biopsy showed vacuolar alterations and a marked accumulation of amiodarone and of its metabolite desethylamiodarone was found in the muscle sample despite normal blood levels. Amiodarone-induced morphological alterations of the muscle may be related to the actual tissue concentration rather than to the blood level.
AB - The case of a 69-year-old woman who developed muscle weakness on chronic amiodarone treatment is reported. Muscle biopsy showed vacuolar alterations and a marked accumulation of amiodarone and of its metabolite desethylamiodarone was found in the muscle sample despite normal blood levels. Amiodarone-induced morphological alterations of the muscle may be related to the actual tissue concentration rather than to the blood level.
KW - Amiodarone
KW - side effects
UR - http://www.scopus.com/inward/record.url?scp=0023549775&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023549775&partnerID=8YFLogxK
U2 - 10.1007/BF02333668
DO - 10.1007/BF02333668
M3 - Article
C2 - 3429219
AN - SCOPUS:0023549775
VL - 8
SP - 603
EP - 608
JO - Italian Journal of Neurological Sciences
JF - Italian Journal of Neurological Sciences
SN - 0392-0461
IS - 6
ER -