Myopathy during amiodarone treatment: a case report

F. Carella; E. Riva; L. Morandi; E. Cappiello; A. Mangoni

doi:10.1007/BF02333668

Myopathy during amiodarone treatment: a case report

F. Carella, E. Riva, L. Morandi, E. Cappiello, A. Mangoni

Research output: Contribution to journal › Article › peer-review

Abstract

The case of a 69-year-old woman who developed muscle weakness on chronic amiodarone treatment is reported. Muscle biopsy showed vacuolar alterations and a marked accumulation of amiodarone and of its metabolite desethylamiodarone was found in the muscle sample despite normal blood levels. Amiodarone-induced morphological alterations of the muscle may be related to the actual tissue concentration rather than to the blood level.

Original language	English
Pages (from-to)	603-608
Number of pages	6
Journal	Italian Journal of Neurological Sciences
Volume	8
Issue number	6
DOIs	https://doi.org/10.1007/BF02333668
Publication status	Published - Dec 1987

Keywords

Amiodarone
side effects

ASJC Scopus subject areas

Neuroscience(all)
Clinical Neurology

Access to Document

10.1007/BF02333668

Cite this

@article{6f62730ac29c4c5eb6d063d4f4a0b40b,

title = "Myopathy during amiodarone treatment: a case report",

abstract = "The case of a 69-year-old woman who developed muscle weakness on chronic amiodarone treatment is reported. Muscle biopsy showed vacuolar alterations and a marked accumulation of amiodarone and of its metabolite desethylamiodarone was found in the muscle sample despite normal blood levels. Amiodarone-induced morphological alterations of the muscle may be related to the actual tissue concentration rather than to the blood level.",

keywords = "Amiodarone, side effects",

author = "F. Carella and E. Riva and L. Morandi and E. Cappiello and A. Mangoni",

year = "1987",

month = dec,

doi = "10.1007/BF02333668",

language = "English",

volume = "8",

pages = "603--608",

journal = "Italian Journal of Neurological Sciences",

issn = "0392-0461",

publisher = "Springer Verlag",

number = "6",

}

TY - JOUR

T1 - Myopathy during amiodarone treatment

T2 - a case report

AU - Carella, F.

AU - Riva, E.

AU - Morandi, L.

AU - Cappiello, E.

AU - Mangoni, A.

PY - 1987/12

Y1 - 1987/12

N2 - The case of a 69-year-old woman who developed muscle weakness on chronic amiodarone treatment is reported. Muscle biopsy showed vacuolar alterations and a marked accumulation of amiodarone and of its metabolite desethylamiodarone was found in the muscle sample despite normal blood levels. Amiodarone-induced morphological alterations of the muscle may be related to the actual tissue concentration rather than to the blood level.

AB - The case of a 69-year-old woman who developed muscle weakness on chronic amiodarone treatment is reported. Muscle biopsy showed vacuolar alterations and a marked accumulation of amiodarone and of its metabolite desethylamiodarone was found in the muscle sample despite normal blood levels. Amiodarone-induced morphological alterations of the muscle may be related to the actual tissue concentration rather than to the blood level.

KW - Amiodarone

KW - side effects

UR - http://www.scopus.com/inward/record.url?scp=0023549775&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023549775&partnerID=8YFLogxK

U2 - 10.1007/BF02333668

DO - 10.1007/BF02333668

M3 - Article

C2 - 3429219

AN - SCOPUS:0023549775

VL - 8

SP - 603

EP - 608

JO - Italian Journal of Neurological Sciences

JF - Italian Journal of Neurological Sciences

SN - 0392-0461

IS - 6

ER -

Myopathy during amiodarone treatment: a case report

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this