TY - JOUR
T1 - Myotonic dystrophy (Steinert disease)
T2 - A morphologic and biochemical hair study
AU - Amorosi, Beatrice
AU - Giustini, Sandra
AU - Rossi, Alfredo
AU - Giacanelli, Manlio
AU - Calvieri, Stefano
PY - 1999
Y1 - 1999
N2 - Background: Myotonic dystrophy is a systemic genetic disorder, with dominant transmittance, it is characterized by generalized progressive muscular abnormality. Although frontoparietal alopecia is one of the most common symptoms in myotonic dystrophy, it has not received much attention. Methods: We examined 25 subjects from two families: 10 patients were affected by Steinert disease and 15 were not. The various morphologic and biochemical hair alteratiOnS are reported. Results: All investigated subjects (affected or not) presented the same type of morphologic and biochemical hair alterations. Conclusions: These findings could be used to construct a hypothesis to explain the cause of the disease.
AB - Background: Myotonic dystrophy is a systemic genetic disorder, with dominant transmittance, it is characterized by generalized progressive muscular abnormality. Although frontoparietal alopecia is one of the most common symptoms in myotonic dystrophy, it has not received much attention. Methods: We examined 25 subjects from two families: 10 patients were affected by Steinert disease and 15 were not. The various morphologic and biochemical hair alteratiOnS are reported. Results: All investigated subjects (affected or not) presented the same type of morphologic and biochemical hair alterations. Conclusions: These findings could be used to construct a hypothesis to explain the cause of the disease.
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U2 - 10.1046/j.1365-4362.1999.00206.x
DO - 10.1046/j.1365-4362.1999.00206.x
M3 - Article
C2 - 10397582
AN - SCOPUS:0032996393
VL - 38
SP - 434
EP - 438
JO - International Journal of Dermatology
JF - International Journal of Dermatology
SN - 0011-9059
IS - 6
ER -