n-Hexane urine elimination and weighted exposure concentration

M. Imbriani, S. Ghittori, G. Pezzagno, E. Capodaglio

Research output: Contribution to journalArticlepeer-review


The concentration of n-hexane in urine was determined in 30 subjects occupationally exposed to n-hexane (median value 59.6 mg/m3) in a shoe factory. The measurement of the substance was performed by means of a Hewlett-Packard 5880 gas chromatograph supplied with a Hewlett-Packard 5970 Mass Selective Detector. The analyses were performed by the head space method (constant volume method, after determination of the urine partition coefficient by the multiple phase equilibration method). The authors found a significant correlation between the n-hexane urine concentrations (μg/1, Cu) and the n-hexane environmental concentrations (mg/m3, Ci) (r = 0.84; Cu = 0.0669 x Ci + 0.8396).

Original languageEnglish
Pages (from-to)33-41
Number of pages9
JournalInternational Archives of Occupational and Environmental Health
Issue number1
Publication statusPublished - Dec 1984


  • Biological monitoring
  • Head space method
  • n-Hexane
  • Urinalysis

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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