TY - JOUR
T1 - Nail lichen striatus
T2 - Clinical features and long-term follow-up of five patients
AU - Tosti, A.
AU - Peluso, A. M.
AU - Misciali, C.
AU - Cameli, N.
PY - 1997
Y1 - 1997
N2 - Background: Nail involvement in lichen striatus (LS) is uncommon and has always been reported in association with typical skin lesions. Objective: We attempted to characterize the clinical and pathologic features and the long- term prognosis of nail LS. Methods: Five cases of LS of the nail including three cases with exclusive nail involvement were evaluated and the literature reviewed. Results: Biopsy specimens showed a moderately dense bandlike lymphohistiocytic infiltrate affecting the proximal nailfold, the nail bed, and the nail matrix dermis. Exocytosis with slight spongiosis, focal hypergranulosis, and dyskeratotic cells were detectable in the nail matrix epithelium. Spontaneous regression of the onychodystrophy occurred after 4 to 12 months from the time of diagnosis (mean, 8.4 months). Conclusion: Nail LS is not necessarily associated with skin lesions but can also be an isolated finding. The diagnosis of nail LS should be strongly suspected when a child or a young patient presents with lichen planus-like nail abnormalities localized to the lateral or medial portion of a single nail.
AB - Background: Nail involvement in lichen striatus (LS) is uncommon and has always been reported in association with typical skin lesions. Objective: We attempted to characterize the clinical and pathologic features and the long- term prognosis of nail LS. Methods: Five cases of LS of the nail including three cases with exclusive nail involvement were evaluated and the literature reviewed. Results: Biopsy specimens showed a moderately dense bandlike lymphohistiocytic infiltrate affecting the proximal nailfold, the nail bed, and the nail matrix dermis. Exocytosis with slight spongiosis, focal hypergranulosis, and dyskeratotic cells were detectable in the nail matrix epithelium. Spontaneous regression of the onychodystrophy occurred after 4 to 12 months from the time of diagnosis (mean, 8.4 months). Conclusion: Nail LS is not necessarily associated with skin lesions but can also be an isolated finding. The diagnosis of nail LS should be strongly suspected when a child or a young patient presents with lichen planus-like nail abnormalities localized to the lateral or medial portion of a single nail.
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U2 - 10.1016/S0190-9622(97)80270-8
DO - 10.1016/S0190-9622(97)80270-8
M3 - Article
C2 - 9204052
AN - SCOPUS:0030942660
VL - 36
SP - 908
EP - 913
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
SN - 0190-9622
IS - 6 I
ER -