Naloxone potentiates shock-induced aggressive behavior in mice

Stefano Puglisi-Allegra, Alberto Oliverio

Research output: Contribution to journalArticlepeer-review


Naloxone (0.025 to 0.05 mg/kg IP) potentiates shock-induced aggressive behavior in C57BL/6 mice but not in DBA/2 mice which do not fight in absence of drug. This effect is not related to pain sensitivity since the doses used in this experiment do not lower tail-flick threshold in C57BL/6 mice. These findings are discussed in terms of the role of the endorphin system and of catecholamine related sensory attention in a number of social interactions in the mouse.

Original languageEnglish
Pages (from-to)513-514
Number of pages2
JournalPharmacology, Biochemistry and Behavior
Issue number3
Publication statusPublished - 1981


  • Endorphins
  • Inbred mice
  • Naloxone
  • Shock-induced aggressive behavior

ASJC Scopus subject areas

  • Biochemistry
  • Behavioral Neuroscience
  • Pharmacology


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