Naloxone potentiation of 2-Br-α-ergocryptine (CB 154) effects on GH secretion in man

L. F. Agnati, R. D'Alessandro, F. Benfenati, P. Cortelli, E. Galassi, M. Capelli

Research output: Contribution to journalArticlepeer-review

Abstract

The effect of the combined administration of either CB 154 (2.5 mg/osM) or L-DOPA (500 mg/osM) and naloxone have been studied in six normal male volunteers. Naloxone cause a clear-cut potentiation of CB 154 effects on human growth hormone (hGH) secretion and only a slight, statistically non-significant, potentiation of L-DOPA effects on hGH secretion. These results have been discussed in the light of morphofunctional findings showing possible interactions between dopamine (DA) systems and somatostatin-positive and enkephalin-positive nerve terminals.

Original languageEnglish
Pages (from-to)229-233
Number of pages5
JournalNeuroscience Letters
Volume15
Issue number2-3
DOIs
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Neuroscience(all)

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