Abstract
In this work we report how cotton fibers can be permanently functionalized with glycidylmethacrylate (GMA) by means of the Fenton's reaction and used for manufacturing biomedical textiles having significant capability to adsorb amoxicillin and vancomycin, two different antibiotics largely used in the clinical activity. The pristine cellulose fibers have no adsorption capability. The adsorption properties of GMA modified cotton fibers are due to their surface nanostructured by the whole of GMA appendages. The reversible adsorption capacity can be modulated by chemical treatments after the grafting of GMA on the cellulose backbone, through the epoxide ring opening by addition of water or primary diamines having different aliphatic chain length (2 to 6 C atoms). Such materials can find suitable application as wounds dressing or more in general for the topical administration of drugs.
Original language | English |
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Title of host publication | Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 |
Pages | 174-177 |
Number of pages | 4 |
Publication status | Published - 2012 |
Event | Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 - Santa Clara, CA, United States Duration: Jun 18 2012 → Jun 21 2012 |
Other
Other | Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 |
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Country/Territory | United States |
City | Santa Clara, CA |
Period | 6/18/12 → 6/21/12 |
Keywords
- Amoxicillin
- Antibacterial textiles
- Cellulose
- Glycidylmethacrylate
- Vancomycin
ASJC Scopus subject areas
- Ceramics and Composites
- Surfaces, Coatings and Films