Nanotechnology Scaffolds for Alveolar Bone Regeneration

Goker Funda, Silvio Taschieri, Giannì Aldo Bruno, Emma Grecchi, Savadori Paolo, Donati Girolamo, Massimo Del Fabbro

Research output: Contribution to journalReview article

Abstract

In oral biology, tissue engineering aims at regenerating functional tissues through a series of key events that occur during alveolar/periodontal tissue formation and growth, by means of scaffolds that deliver signaling molecules and cells. Due to their excellent physicochemical properties and biomimetic features, nanomaterials are attractive alternatives offering many advantages for stimulating cell growth and promoting tissue regeneration through tissue engineering. The main aim of this article was to review the currently available literature to provide an overview of the different nano-scale scaffolds as key factors of tissue engineering for alveolar bone regeneration procedures. In this narrative review, PubMed, Medline, Scopus and Cochrane electronic databases were searched using key words like "tissue engineering", "regenerative medicine", "alveolar bone defects", "alveolar bone regeneration", "nanomaterials", "scaffolds", "nanospheres" and "nanofibrous scaffolds". No limitation regarding language, publication date and study design was set. Hand-searching of the reference list of identified articles was also undertaken. The aim of this article was to give a brief introduction to review the role of different nanoscaffolds for bone regeneration and the main focus was set to underline their role for alveolar bone regeneration procedures.

Original languageEnglish
Article numberE201
JournalMaterials
Volume13
Issue number1
DOIs
Publication statusPublished - Jan 3 2020

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