Abstract
Study Objectives: To assess the prevalence of sleep related-eating disorder (SRED ) and nocturnal smoking (NS) in patients with narcolepsy with cataplexy (NC). Design: Case-control study. Setting: University hospital. Patients or Participants: 65 consecutive adult NC patients (33 men; mean age 43.9 ± 19.2 years) and 65 age-, sex-, and geographical origin-matched controls. Interventions: Validated questionnaires were used to investigate SRED , NS, restless legs syndrome (RLS ), and psychopathological traits (using Eating Disorder Inventory-2 [EDI-2]; Maudsley Obsessive-Compulsive Inventory [MOCI]; and Beck Depression Inventory [BDI]). Measurements and Results: NC patients showed a higher prevalence of SRED (32% vs 3%, P = 0.00001), NS (21% vs 0%, P = 0.00006), and RLS (18% vs 5%, P = 0.013) than controls. Moreover, NC patients presented more frequently with an eating-related pathological profile on the EDI-2 (80% vs 46%, P = 0.00006) and had a higher prevalence of depressed mood on the BDI (41% vs 18%, P = 0.004). In comparison to patients without SRED, NC patients with SRED were more frequently women (71% vs 39%, P = 0.013), had higher "bulimic" (29% vs 2%, P = 0.004) and "social insecurity" (48% vs 18%, P = 0.013) traits on the EDI-2, had higher obsessive-compulsiveness on the MOCI (29% vs 4%, P = 0.009), and were more depressed on the BDI (67% vs 29%, P = 0.005). NC patients with NS showed more frequent pathological profiles on the EDI-2 (100% vs 75%, P = 0.035), including the "bulimic" (29% vs 6%, P = 0.015), "perfectionism" (43% vs 14%, P = 0.016), and "social insecurity" (50% vs 22, P = 0.035) profiles. Conclusion: Our study shows a strong association of the compulsive nocturnal behaviors SRED and NS with adult NC.
| Original language | English |
|---|---|
| Pages (from-to) | 1365-1371 |
| Number of pages | 7 |
| Journal | Sleep |
| Volume | 34 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 1 2011 |
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Keywords
- Case-control study
- Narcolepsy with cataplexy
- Nocturnal compulsive behaviors
- Nocturnal smoking
- Sleep related-eating disorder
ASJC Scopus subject areas
- Physiology (medical)
- Clinical Neurology
Cite this
Narcolepsy with cataplexy associated with nocturnal compulsive behaviors : A case-control study. / Palaia, Vincenzo; Poli, Francesca; Pizza, Fabio; Antelmi, Elena; Franceschini, Christian; Moghadam, Keivan Kaveh; Provini, Frederica; Pagotto, Uberto; Montagna, Pasquale; Schenck, Carlos H.; Mignot, Emmanuel; Plazzi, Giuseppe.
In: Sleep, Vol. 34, No. 10, 01.10.2011, p. 1365-1371.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Narcolepsy with cataplexy associated with nocturnal compulsive behaviors
T2 - A case-control study
AU - Palaia, Vincenzo
AU - Poli, Francesca
AU - Pizza, Fabio
AU - Antelmi, Elena
AU - Franceschini, Christian
AU - Moghadam, Keivan Kaveh
AU - Provini, Frederica
AU - Pagotto, Uberto
AU - Montagna, Pasquale
AU - Schenck, Carlos H.
AU - Mignot, Emmanuel
AU - Plazzi, Giuseppe
PY - 2011/10/1
Y1 - 2011/10/1
N2 - Study Objectives: To assess the prevalence of sleep related-eating disorder (SRED ) and nocturnal smoking (NS) in patients with narcolepsy with cataplexy (NC). Design: Case-control study. Setting: University hospital. Patients or Participants: 65 consecutive adult NC patients (33 men; mean age 43.9 ± 19.2 years) and 65 age-, sex-, and geographical origin-matched controls. Interventions: Validated questionnaires were used to investigate SRED , NS, restless legs syndrome (RLS ), and psychopathological traits (using Eating Disorder Inventory-2 [EDI-2]; Maudsley Obsessive-Compulsive Inventory [MOCI]; and Beck Depression Inventory [BDI]). Measurements and Results: NC patients showed a higher prevalence of SRED (32% vs 3%, P = 0.00001), NS (21% vs 0%, P = 0.00006), and RLS (18% vs 5%, P = 0.013) than controls. Moreover, NC patients presented more frequently with an eating-related pathological profile on the EDI-2 (80% vs 46%, P = 0.00006) and had a higher prevalence of depressed mood on the BDI (41% vs 18%, P = 0.004). In comparison to patients without SRED, NC patients with SRED were more frequently women (71% vs 39%, P = 0.013), had higher "bulimic" (29% vs 2%, P = 0.004) and "social insecurity" (48% vs 18%, P = 0.013) traits on the EDI-2, had higher obsessive-compulsiveness on the MOCI (29% vs 4%, P = 0.009), and were more depressed on the BDI (67% vs 29%, P = 0.005). NC patients with NS showed more frequent pathological profiles on the EDI-2 (100% vs 75%, P = 0.035), including the "bulimic" (29% vs 6%, P = 0.015), "perfectionism" (43% vs 14%, P = 0.016), and "social insecurity" (50% vs 22, P = 0.035) profiles. Conclusion: Our study shows a strong association of the compulsive nocturnal behaviors SRED and NS with adult NC.
AB - Study Objectives: To assess the prevalence of sleep related-eating disorder (SRED ) and nocturnal smoking (NS) in patients with narcolepsy with cataplexy (NC). Design: Case-control study. Setting: University hospital. Patients or Participants: 65 consecutive adult NC patients (33 men; mean age 43.9 ± 19.2 years) and 65 age-, sex-, and geographical origin-matched controls. Interventions: Validated questionnaires were used to investigate SRED , NS, restless legs syndrome (RLS ), and psychopathological traits (using Eating Disorder Inventory-2 [EDI-2]; Maudsley Obsessive-Compulsive Inventory [MOCI]; and Beck Depression Inventory [BDI]). Measurements and Results: NC patients showed a higher prevalence of SRED (32% vs 3%, P = 0.00001), NS (21% vs 0%, P = 0.00006), and RLS (18% vs 5%, P = 0.013) than controls. Moreover, NC patients presented more frequently with an eating-related pathological profile on the EDI-2 (80% vs 46%, P = 0.00006) and had a higher prevalence of depressed mood on the BDI (41% vs 18%, P = 0.004). In comparison to patients without SRED, NC patients with SRED were more frequently women (71% vs 39%, P = 0.013), had higher "bulimic" (29% vs 2%, P = 0.004) and "social insecurity" (48% vs 18%, P = 0.013) traits on the EDI-2, had higher obsessive-compulsiveness on the MOCI (29% vs 4%, P = 0.009), and were more depressed on the BDI (67% vs 29%, P = 0.005). NC patients with NS showed more frequent pathological profiles on the EDI-2 (100% vs 75%, P = 0.035), including the "bulimic" (29% vs 6%, P = 0.015), "perfectionism" (43% vs 14%, P = 0.016), and "social insecurity" (50% vs 22, P = 0.035) profiles. Conclusion: Our study shows a strong association of the compulsive nocturnal behaviors SRED and NS with adult NC.
KW - Case-control study
KW - Narcolepsy with cataplexy
KW - Nocturnal compulsive behaviors
KW - Nocturnal smoking
KW - Sleep related-eating disorder
UR - http://www.scopus.com/inward/record.url?scp=80053514904&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80053514904&partnerID=8YFLogxK
U2 - 10.5665/SLEEP.1280
DO - 10.5665/SLEEP.1280
M3 - Article
C2 - 21966068
AN - SCOPUS:80053514904
VL - 34
SP - 1365
EP - 1371
JO - Sleep
JF - Sleep
SN - 0161-8105
IS - 10
ER -