Nasal brushing: A clinically useful procedure in pediatric patients with rhinosinusitis?

Oliviero Sacco, Vincenzo Tarantino, Sabina Lantero, Michela Silvestri, Daniela Spallarossa, Maria Ausilia Barretta, Bruno Fregonese, Giovanni A. Rossi

Research output: Contribution to journalArticlepeer-review


Sinusitis is a common complication of non-allergic and allergic rhinitis, and can trigger lower respiratory diseases, such as bronchitis and asthma. Standard radiography is unable to give any data about the underlying pathological mechanisms (infectious or allergic) involved and infectious rhinosinusitis is very common in pediatric age, even in allergic patients. We investigated the possibility of obtaining more useful diagnostic information, performing nasal brushing (NB) on 117 children with recurrent respiratory symptoms. The following hypothesis were evaluated: (1) whether NB neutrophil/eosinophil percentages and/or NB culture could predict the radiological evidence of maxillary sinusitis; and (2) whether differences between nonallergic and allergic patients could be detected. In the total patient group and in the nonallergic group, the comparison of NB neutrophil percentages in patients with and without maxillary sinusitis showed a statistically significant difference (median 2 and 18%, respectively; P

Original languageEnglish
Pages (from-to)23-30
Number of pages8
JournalInternational Journal of Pediatric Otorhinolaryngology
Issue number1
Publication statusPublished - Oct 15 1999


  • Asthma
  • Bronchitis
  • Nasal brushing
  • Rhinosinusitis
  • Upper respiratory infections

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine
  • Surgery


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