Nasal eosinophils correlate with FEV1 in patiens with perennial allergic rhinitis associated to asthma

G. Ciprandi, M. Milanese, M. A. Tosca, I. Cirillo, A. Vizzaccaro, V. Ricca

Research output: Contribution to journalArticle

Abstract

Background: Eosinophil inflammation is present in nasal and bronchial mucosa and a clear link between upper and lower airways exists. Our aim was to evaluate whether nasal inflammation correlates with lung function in patients with perennial allergic rhinitis associated with asthma. Methods: Eighty perennial allergic rhinitics with mild asthma, aged from 18 to 46 years, were enrolled. Nasal scraping and spirometry were performed in all subjects. Results: A close relationship between the nasal eosinophil number and the percentage of predicted FEV1 was demonstrated (r= -0.76; p

Original languageEnglish
Pages (from-to)363-365
Number of pages3
JournalEuropean Annals of Allergy and Clinical Immunology
Volume36
Issue number10
Publication statusPublished - Dec 2004

Keywords

  • FEV
  • Mild asthma
  • Nasal eosinophils
  • Perennial allergic rhinitis

ASJC Scopus subject areas

  • Immunology and Allergy

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