National validation and proposed revision of REM sleep behavior disorder screening questionnaire (RBDSQ)

Sara Marelli, Paola M. V. Rancoita, Federica Giarrusso, Andrea Galbiati, Marco Zucconi, Alessandro Oldani, Clelia Di Serio, Luigi Ferini Strambi

Research output: Contribution to journalArticle

Abstract

We validated the Italian version of the rapid eye movement sleep behavior disorder (RBD) screening questionnaire (RBDSQ) and calculated its cut-off value for discriminating RBD group from other sleep disorders and healthy controls (HC). 380 patients with sleep disorders and 101 HC were enrolled. RBDSQ achieved an acceptable Cronbach’s α value of 0.787 and item 10 was the only one with a very low item-total biserial correlation (0.141). At ROC analysis, we obtained an AUC of 0.888, denoting a good performance of the RBDSQ total score for predicting the RBD status. The optimal cut-off value was 8 and it achieved good values of both sensitivity and specificity (0.842 and 0.780, respectively). Due to the poor performance of item 10 in our sample, we analyzed the RBDSQ without this item (called “revised RBDSQ”). We obtained a good Cronbach’s α of 0.802. When evaluating the performance of the revised score in predicting the RBD status, we obtained an increased value of AUC (0.899). The optimal cut-off value was still 8 (sensitivity = 0.829; specificity = 0.820). The Italian version of RBDSQ is a sensitive tool for the identification of RBD patients. An improvement of the instrument could be obtained by removing item 10 and define a higher cut-off value of 8. The “revised RBDSQ” represents a reliable screening questionnaire for primary care physicians and neurologists and its employment may facilitate the choice of subjects that should undergo a PSG that confirms the diagnosis of RBD, thus avoiding polysomnographic exams when not needed.
Original languageEnglish
Pages (from-to)2470 - 2475
Number of pages6
JournalJournal of Neurology
Volume263
Issue number12
DOIs
Publication statusPublished - Dec 1 2016

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REM Sleep Behavior Disorder
Area Under Curve
Sensitivity and Specificity
Surveys and Questionnaires
Primary Care Physicians
ROC Curve

Keywords

  • Parasomnia
  • Questionnaire
  • RBDSQ
  • REM sleep behavior disorder

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

National validation and proposed revision of REM sleep behavior disorder screening questionnaire (RBDSQ). / Marelli, Sara; Rancoita, Paola M. V.; Giarrusso, Federica; Galbiati, Andrea; Zucconi, Marco; Oldani, Alessandro; Di Serio, Clelia; Ferini Strambi, Luigi.

In: Journal of Neurology, Vol. 263, No. 12, 01.12.2016, p. 2470 - 2475.

Research output: Contribution to journalArticle

Marelli, Sara ; Rancoita, Paola M. V. ; Giarrusso, Federica ; Galbiati, Andrea ; Zucconi, Marco ; Oldani, Alessandro ; Di Serio, Clelia ; Ferini Strambi, Luigi. / National validation and proposed revision of REM sleep behavior disorder screening questionnaire (RBDSQ). In: Journal of Neurology. 2016 ; Vol. 263, No. 12. pp. 2470 - 2475.
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