@inbook{45b4ffda02214cb0a9ea0f150f7b788f,
title = "Natural antibodies to tumor-associated antigens",
abstract = "Natural autoantibodies raised by humoral immune response to cancer can be exploited to identify potential tumor-associated antigens (TAAs), and might constitute new putative prognostic and/or diagnostic biomarkers. Here we describe how sera from tumor patients can be used to identify TAAs by screening antibody immunoreactivity against the cancer proteome resolved by two-dimensional gel electrophoresis.",
keywords = "2D-electrophoresis, Autoantibodies, Immunoproteomics, Tumor-associated antigens, Western blot",
author = "{\'A}lvarez-Fern{\'a}ndez, {Sheila Mar{\'i}a} and {De Monte}, Lucia and Massimo Alessio",
year = "2016",
month = apr,
day = "1",
doi = "10.1007/978-1-4939-3338-9_2",
language = "English",
volume = "1393",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "11--25",
booktitle = "Methods in Molecular Biology",
}